Research Journal of Microbiology1816-4935xxxx-xxxxScience International10.3923/jm.2009.366.369In vitro Activity of Some Antimicrobial Agents against Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus in Khartoum, Sudan]]>SaeedH.A. AhmedW.B. 102009410Staphylococcus aureus is a causative agent of many types of diseases throughout the world. Patients hospitalized for long period of time usually are predisposed to infection by methicillin resistant S. aureus (MRSA). The objectives of the present study were to evaluate the efficacy of some antimicrobial agents against S. aureus and MRSA and to select the most effective antibiotic. Clinical specimens were collected from patients with wounds and/or urinary tract infections. The specimens were proceeded for isolation of the pathogens. Identification was done by conventional methods. Antimicrobial sensitivity test was carried out using modified Kirby-Bauer Disc Diffusion Technique in accordance with National Committee on Clinical Laboratory Standards (NCCLS). Of 163 S. aureus recovered, 15 (9.2%) isolates were MRSA. The most effective antimicrobial agent against both S. aureus and MRSA was vancomycin (99%). The activity of the rest antimicrobial agents was cephalexin, 92%, methicillin, 90%, cloxacillin 33%, penicillin 14% and amoxicillin 10%. It is concluded that vancomycin may be an alternative antibiotic for patients with wound and/or urinary tract infections caused by S. aureus or MRSA.]]>Pillar, C.M., M.K. Aranza, D. Shah and D.F. Sahm,2008In vitro activity profile of ceftobiprole, an anti-MRSA cephalosporin against recent Gram-positive and Gram-negative isolates of European origin.]]>61595602Neela, V., M. Sasikumar, G.R. Ghaznavi, S. Zamberi and S. Mariana,2008In Vitro Activities of 28 Antimicrobial Agents Against Methicillin-Resistant Staphylococcus aureus (MRSA) from Clinical Setting in Malaysia.]]>39885892Tacconelli, E., G. De Angelis, M.A. Cataldo, E. Pozzi and R. Cauda,2008Staphylococcus aureus (MRSA) isolation? A systematic review and meta-analysis.]]>612638Barrow, G.I. and R.K.A. Feltham,20033rd Edn.,pp: 352pp: 352NCCLS,19976th Edn.,WHO.,19976th Edn.,Murray, P.R., E.J. Baron, M.A. Pfaller, F.C. Tenover and R.H. Yolke,20079th Edn.,Mackie, T.J. and McCarteny,1996pp: 157pp: 157Cooper, C. and M.A. Ochola,20032003Tambekar, D.H., D.V. Dhanorkar, S.R. Gulhane and M.N. Dudhane,2009Staphylococcus aureus from healthcare and community associated sources.]]>15256