Research Journal of Microbiology1816-4935xxxx-xxxxScience International10.3923/jm.2008.588.594 Cissus repanda Vahl. Plant Extract on Herpes Simplex Virus]]>NikomtatJiraporn ThongwaiNarumol LumyongSaisamorn TragoolpuaYingmanee 9200839The effect of Cissus repanda Vahl. plant extract
on herpes simplex virus type 1 and type 2 was investigated in this study.
The cytotoxicity of dichloromethane and methanol extracts of C. repanda
on GMK cells was determined by MTT assay. Non toxic concentrations were
used in the study. Methanol extracts of C. repanda showed higher
anti-HSV efficacy than dichloromethane extracts, by plaque reduction assay,
although, HSV particles were directly inhibited by both extracts. Inhibition
of HSV attachment, penetration and replication were also observed, after
treatment of HSV with C. repanda extracts. The most affected stage
was the attachment period. Moreover, C. repanda extracts inhibited
replication of HSV-2 more than HSV-1.]]>Akanitapichat, P., A. Wangmaneerat, P. Wilairat and K.F. Bastow,2006Dunbaria bella Prain.]]>1056468Chattawanith, B.,1997Cissus repanda.]]>1997pp: 105pp: 105Cheng, H.Y., C.C. Lin and T.C. Lin,2002Terminalia arjuna Linn.]]>55447455Fukuchi, K., H. Sakagami, T. Okuda, T. Hatano and S. Tanuma et al.,198911285297Galvis, L.B., C. Zuluaga, M. Arno, M.A. González and R.J. Zaragozá,2001in vitro antiviral and cytotoxic activity of semisynthetic analogues of Scopadulane diterpenes.]]>6413181321Hammer, S.M. and R.T. Inouye,19971997pp: 186-201pp: 186-201Kurokawa, M., K. Nagasaka, T. Hirabayashi, S. Uyama and H. Sato et al.,1995in vitro and in vivo.]]>271937Larsson, P.A., J.M. Hirsch, J.S. Gronovitz and A. Vahlne,199237969978De Logu, A., G. Loy, M.L. Pellerano, L. Bonsignore and M.L. Schivo,2000Santolina insularis essential oil.]]>48177185Ryu, S.Y., C.K. Lee, J.W. Ahu, S.H. Lee and O.P. Zee,199316339342Schuhmacher, A., J. Reichling and P. Schnitzler,2003in vitro.]]>10504510Sydiskis, R.J., D.G. Owen, J.L. Lohr, K.H. Rosler and R.N. Blomster,19913524632466Tragoolpua, Y. and A. Jatisatienr,2007Eugenia caryophyllus (Spreng.) Bullock and S.G.Harrison and essential oil, eugenol.]]>2111531158Tyring, S.K.,199820661670Wiyakrutta, S., N. Sriubolmas, W. Panphut, N. Thongon, K. Danwisetkanjana, N. Ruangrungsi and V. Meevootisom,200420265272Yang, C.M., H.Y. Cheng, T.C. Lin, L.C. Chiang and C.C. Lin,2005Phyllanthus urinaria inhibit HSV-2 infection in vitro.]]>672430Yoosook, C., Y. Panpisutchai, S. Chaichana, T. Santisuk and V. Reutrakul,1999Barleria lupulina and Clinacanthus nutans.]]>67179187Yoosook, C., N. Bunyapraphatsara, Y. Boonyakiat and C. Kuntasuk, 20006411419Yu, Z., W. Li and F. Liu,2004215159166