Research Journal of Microbiology1816-4935xxxx-xxxxScience International10.3923/jm.2007.445.453BahadorN. BaserisalehiM. KapadnisB. P.5200725A bacteriophage is type of virus, which can infects bacteria, either kill a bacterial cell or integrate its DNA into the host bacterial chromosome. For the first time dHerelle called the virus bacteriophage or bacteria-eater. Phages can replicate only inside host cells. They are associated with most bacterial families and use the ribosomes, protein-synthesizing factors, amino acids and energy-generating systems of the host cell to replicate. Indeed, phages can multiply only in metabolizing host bacteria. Nowadays, using bacteriophage in different purpose viz., phage typing, Phages as indicators, as food preservatives and decontaminants, transducer and therapeutic agents considered as tremendous investigate to make facility for human being. 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