Research Journal of Microbiology1816-4935xxxx-xxxxScience International10.3923/jm.2007.392.396Dioclea reflexa, Mucuna pruriens, Ficus asperifolia and Tragia spathulata]]>OgundareA. O.OlorunfemiO. B.4200724The antimicrobial activity of crude ethanolic, methanolic and acetonic leaf extracts of Dioclea reflexa (J.D. Hooker), Mucuna pruriens (Linn), Ficus asperifolia (Miq.) and Tragia spathulata (Benth) was investigated against nine microorganisms including Staphylococcus aureus, Proteus mirabilis, Klebsiella pneumoniae, Salmonella typhi, Streptococcus pneumoniae, Escherichia coli, Candida albicans, Aspergillus flavus and Fusarium solani. Extracts of Dioclea reflexa showed broad spectrum antibacterial activity, having the highest inhibitory action on the bacterial isolates. Mucuna pruriens, Ficus. asperifolia and Tragia spathulata had lower antimicrobial potency when compared to the extracts of Dioclea reflexa. The Minimum Inhibitory Concentration (MIC) of Dioclea reflexa against Proteus mirabilis and Klebsiella pneumoniae was 5 mg mL-1 while the MIC for the other bacteria was 10 mg mL-1. However, the least MIC value (10 mg mL-1) was recorded with methanol and acetone extracts of Dioclea reflexa. The MIC of extracts from Mucuna pruriens, Ficus sperifolia and Tragia spathulata ranged between 24 and 25 mg mL-1. Phytochemical analysis of the extracts of Dioclea reflexa showed the presence of alkaloids, tannins, phenols and glycosides. All the other plants had phenols, tannins and glycosides,except Tragia spathulata which also have alkaloids.]]>Yenesew, A., S. Derese, J.O. Midiwo, C.C. Bii, M. Heydenreich and M.G. Peter,2005Erythrina burttii.]]>76469472Ahmad, I. and A.Z. Beg,200174113123Boakye-Yindom, K.,197927880Garrod, L.P., H.P. Lambert and F. O`Gray,19754th Edn.,pp: 501-512pp: 501-512Huffman, M.A.,200151651661Khan, M.R. and A.D. Omoloso,2002Barringtonia asiatica.]]>73255260Mandal, P., S.P.S. Babu and N.C. Mandal,2005Acacia auriculiformis.]]>76462465Olutiola, P.O., O. Famurewa and H.G. Sonntag,19911st Edn.,pp: 62pp: 62Sofowora, A.,19821st Edn.,Pieters, L. and A.J. Vlietinck,20051005760Pieters, L. and A.J. Vlietinck,20051005760