Research Journal of Microbiology1816-4935xxxx-xxxxScience International10.3923/jm.2007.327.336Pseudomonas sp.]]>GummadiSathyanarayana N.LionelAnath C.DashSwati S.GokulakrishnanS. 4200724The effect of glucose on caffeine degradation by Pseudomonas sp., which was previously isolated in our laboratory, was investigated. Caffeine degradation was inhibited when glucose was present in free form in the medium and at a concentration > 1 g L-1. Two-stage culture experiments indicated that glucose probably interferes with the induction of the enzymes involved in the caffeine degradation pathway. The addition of glucose at start and early stages of growth resulted in complete inhibition of caffeine degradation whereas addition at later stages of growth has no inhibitory effect further confirming the inhibitory effect of glucose is due suppression of caffeine catabolising enzyme, which is suggestive of catabolite repression. These findings are novel and have not been reported in other Pseudomonas peptide strains degrading caffeine.]]>Asano, Y., T. Komeda and H. Yamada,19935712861289Blecher, R. and F. Lingens,1977Pseudomonas putida strain.]]>358807817Bressani, R.,19871987pp: 83-88pp: 83-88Collier, D.N., P.W. Hager and P.V. Phibbs Jr.,1996147551561Cooper, C., E.J. Atkinson, H.W. Wahner, W.M. O'Fallon, B.L. Riggs, H.L. Judd and L.J. Melton,19927465471Dash, S.S. and S.N. Gummadi,2006Pseudomonas sp. NCIM 5235.]]>1115123Dash, S.S. and S.N. Gummadi,20062819932002Fakhruddin, A.N.M. and B. Quilty,2005Pseudomonas putida CP1.]]>2115411548Gokulakrishnan, S. and S.N. Gummadi,2006Pseudomonas sp. GSC 1182.]]>4114171421Gokulakrishnan, S., K. Chandraraj and S.N. Gummadi,200537225232Gokulakrishnan, S., K. Chandraraj and S.N. Gummadi,2007Pseudomonas sp. GSC 1182.]]>113346350Gummadi, S.N. and D. Santosh,2006Pseudomonas sp. increase the degradation of caffeine.]]>1561571Holtel, A., S. Marques, I. Mohler, U. Jakubzik and K.N. Timmis,1994xyl operon expression of the Pseudomonas peptide TOL plasmid.]]>17617731776James, J.E.,2004666371Khan, R. and D.C. Straney,1999Nectria haematococca MPVI in culture and during pathogenesis of pea.]]>8733742McFall, S.M., B. Abraham, C.G. Narsolis and A.M. Chakrabarty,199717967296735Miller, G.L.,195931426428Muller, C., L. Petruschka, H. Cuypers, G. Burchardt and H. Herrmann,1996Pseudomonas peptide is mediated by the inhibition of the activator protein PhlR.]]>17820302036Naidu, G.S., I.Y. Lee, O.K. Cho and Y.H. Park,2001Achromobacter cycloclast.]]>26309315Ogunseitan, O.A.,2002Pseudomonas peptide ATCC 700097.]]>18423428Vicente, M. and J.L. Canovas,1973Pseudomonas peptide: physiological role of alternative routes from the analysis of defective mutants.]]>116908914Woolfolk, C.A.,1975Pseudomonas putida strain isolated by enrichment on caffeine as the sole source of carbon and nitrogen.]]>12310881106