Journal of Fisheries and Aquatic Science1816-49271996-0751Academic Journals Inc.10.3923/jfas.2015.323.336Barbonymus gonionotus) and on its Culture Environment]]>IslamM.J. RasulM.G. KashemM.A. HossainM.M. LizaA.A. SayeedM.A. HossainM. Motaher 52015105Studies were conducted to investigate impacts of oxytetracycline on Barbonymus gonionotus muscle. Oxytetracycline the most widely used antibiotics, was fed to Barbonymus gonionotus with 4 g kg1 rate through diet for 45 days. Growth rate was observed for different concentrations of oxytetracycline. Water quality parameters and bacterial quantification were observed for a period of 21 days. Pond water, sediment and fish muscle were tested before and after oxytetracycline medicated feeding. Before feeding of oxytetracycline medicated feed, there was no oxytetracycline in water, sediment and fish muscles. After 2 days of feeding the initial oxytetracycline accumulation was 5070.0 ppb, which reduced considerably to 1190.0 ppb after 20 days from end of medicated diet feeding and not detected after 42 days. Physico-chemical parameters of pond water were determined. Before treatment dissolve oxygen, pH and total hardness of fish pond was 4.516±0.25 mg L1, 7.413±0.09 and 822.33±1.52 ppm, respectively. After 21 days of study period, reached to 5.27±0.025 mg L1, 7.773±0.04 and 769.66±2.08 ppm. It indicates a little change after 21 days. Before oxytetracycline treatment, bacterial load in Barbonymus gonionotus pond was 9.417±0.035×103 CFU g1 in water, 7.31±0.04×107 CFU g1 in sediment, 6.51±0.04×06 CFU g1 in fish gills and 8.52±0.035×107 CFU g1 in fish intestine, which was significantly reduced to 5.28±0.02×103 CFU g1 in water, 2.91±0.02×107 CFU g1 in sediment, 2.21±0.02×106 CFU g1 in gills and 2.39±0.02×107 CFU g1 in intestine.]]>Al-Harbi, A.H. and M.N. 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