Journal of Biological Sciences1727-30481812-5719Asian Network for Scientific Information10.3923/jbs.2014.515.520Padina pavonica Extracts]]>HusniAmir WijayantiRenita Ustadi 82014148The objective of this study was to determine the potential of polyphenols and
phlorotannins extract from Padina pavonica in inhibiting α-amylase
and α-glucosidase. Total phenolic content of P. pavonica was 17.63±0.25
μg GAE/mg extract and total phlorotannins content was 1.94±0.19 μg PGE/mg extract.
The results showed that polyphenols (IC50 = 0.36±0.05 mg mL-1)
and phlorotannins (IC50 = 0.25±0.02 mg mL-1) can
inhibit α-amylase, but lower than acarbose (IC50 = 0.06±0.00
mg mL-1). Polyphenols (IC50 = 26.57±2.08 mg mL-1)
and phlorotannins (IC50 = 34.40±5.93 mg mL-1) can
also inhibit α-glucosidase but also lower than acarbose (IC50
= 1.74±0.25 mg mL-1). Both polyphenol and phlorotannin extracts
from P. pavonica have higher inhibitory activity of α-amylase than
α-glucosidase. There were high correlations between total phenolic and
phlorotannin contents with inhibition activity of α-amylase and α-glucosidase.]]>American Diabetes Association,201235S64S71Al-Mola, H.F.,2009Cymbella spp.]]>2304308Apostolidis, E., P.D. Karayannakidis, Y.I. Kwon, C.M. Lee and N.P. Seeram,2011Ascophyllum nodosum.]]>66313319Chkhikvishvili, I.D. and Z.M. Ramazanov,200036289291Connan, S., E. Deslandes and E.A. Gall,2007349359369Damongilala, L.J., S.B. Widjanarko, E. Zubaidah and M.R.J. Runtuwene,2013Eucheuma cotonii and E. spinosum collected from North Sulawesi waters, Indonesia.]]>17713Elekofehinti, O.O., J.P. Kamdem, I.J. Kade, J.B.T. Rocha and I.G. Adanlawo,2013Solanum anguivi Lam. fruits in alloxan-induced diabetic rats.]]>885661Firdaus, M.,2011Sargassum echinocarpum) as preventive on dysfunction of endothelium cell in aorta of diabetes mellitus rats.]]>2011Firdaus, M., I. Sarwono, D. Muchtadi, M. Astawan, S. Waspadji, T. Wresdiyati and S.K. Setyawati,201021151157, (In Indonesian)Fleury, B.G., A. Kelecom, R.C. Pereira and V.L. Teixeira,1994Dictyotales and Fucales (Phaeophyta).]]>37457462Holdt, S.L. and S. Kraan,201123543597Jormalainen, V. and T. Honkanen,2004Fucus vesiculosus.]]>17807820Kang, C., Y.B. Jin, H. Lee, M. Cha and E.T. Sohn et al.,2010Ecklonia cava attenuates type 1 diabetes by activating AMPK and Akt signaling pathways.]]>48509516Khaled, N., M. Hiba and C. Asma,2012Padina pavonica and Sargassum vulgare from the Lebanese Mediterranean coast.]]>64248Koivikko, R., J. Loponen, T. Honkanen and V. Jormalainen,2005Fucus vesiculosus, with implications on their ecological functions.]]>31195212Raju, S.N., D.S. Kumar, D. Banji, A. Harani, P. Shankar, P.A. Kumar and V.R. Reddy,2010Piper trioicum on amylase, lipase and α-glucosidase.]]>2 237244Lopes, G., C. Sousa, L.R. Silva, E. Pinto and P.B. Andrade et al.,20122012Mayur, B., S. Sandesh, S. Shruti and S. Sung-Yum,2010Carpesium abrotanoides L.]]>415471553Nwosu, F., J. Morris, V.A. Lund, D. Stewart, H.A. Ross and G.J. McDougall,201112610061012De Paula, J.C., M.A. Vallim and V.L. Teixeira,2011Dictyotaceae (Phaeophyceae).]]>21216228SenthilKumar, P. and S. Sudha,20123128130Shibata, T., S. Kawaguchi, Y. Hama, M. Inagaki, K. Yamaguchi and T. Nakamura,200416291296Ye, H., C. Zhou, Y. Sun, X. Zhang, J. Liu, Q. Hu and X. Zeng,2009in vitro of ethanol extract from brown seaweed Sargassum pallidum.]]>230101109You, Q., F. Chen, X. Wang, Y. Jiang and S. Lin,201246164168Zubia, M., D.Y. Robledo and Y. Freile-Pelegrin,200719449458IDF.,20122012WHO.,20122012