Journal of Biological Sciences1727-30481812-5719Asian Network for Scientific Information10.3923/jbs.2010.440.447OsamorV.C. 52010105The aim of this study is to conduct a comparative study of malaria infections in endemic areas of Asia and Africa and to proffer new strategies that will be useful in curtailing the disease. Malaria varies greatly around the world in the level of intensity, in the mosquito vectors that transmit it and in the species causing the disease. P. vivax appears to be more widespread among 20 countries in Asia while the fatal P. falciparum are widely spread in about 50 countries in Africa. A keen observation around most hospitals in Nigeria and Africa in general show that many patients are plagued by malaria as it accounts to the highest percentage of in- patient and out-patient treatment cases, compared to other diseases. Africa including parts of Asia suffers infrastructural decay and poverty occasioned by malaria burden which seems to have defiled many solutions for complete eradication. The method employed specific comparative studies along the line of geographical distribution and etiology to determine the spread, use socio-economic mobility assessment and behavioural risk factors to distinguish situation in both Asia and Africa. Also we considered commitments in local control efforts around the continents of Asia and Africa. While noting that P. vivax is more prevalent in Asia than in Africa where P.falciparium is common we conclude that an assessment of global initiative impacts are notable in more in Africa and the trend of mobility of Asians for economic reasons tend to increase their susceptibility rate to the infection. Due to comparative differences between African and Asian regions as addressed in this work, the translation of global malaria control strategy into regional and country-specific strategies will help bring a modified implementation of unique and beneficial control techniques for the disease eradication.]]>Ajaiyeoba, E., J. Ashidi, O. Abiodun, L. Okpako and O. Ogbole et al.,2004In vitro antiplasmodial activity of seven plants identified in the Nigeria middle belt.]]>42588591Ajayi, I.O., C.O. Falade, E.A. Bamgboye, A.M.J. Oduola and O.O. Kale,200872424Bathurst, I.,20082008Bojang, K.A., P.J.M. Milligan, M. Pinder, L. Vigneron and A. Alloueche et al.,2001Plasmodium falciparum infection in semi-immune adult men in The Gambia: A randomised trial.]]>35819271934Bonjean, K., M.C. De Pauw-Gillet, M.C. Defresne, P. Colson and C. Houssier et al.,19993751365146Boye, G.L. and O. Ampofo,1983Cryptolepis sanguinolenta (Asclepiadaceae).]]>1983pp: 3740Breman, J.G., 200164111Hughes, B., 201098992Cimanga, K., T. DeBruyne, L. Pieters and A.J. Vlietinck,1997In vitro and in vivo antiplasmodial activity of cryptolepine and related alkaloids from Cryptolepis sanguinolenta.]]>60688691Coppi, A., C. Pinzon-Ortiz, C. Hutter and P. Sinnis,2005Plasmodium circumsporozoite protein is proteolytically processed during cell invasion.]]>2012733Daramola, J.O., V.C. Osamor and O.O. Oluwagbemi,20087260267Fehintola, F.A., A.A. Adedeji, S.T. Balogun and A. Sowunmi,2007712901296Feyisetan, B.J., S. Asa and J.A. Ebigbola,19977221234Gordon, D.M., T.W. McGovern, U. Krzych, J.C. Cohen and I. Schneider et al.,1995Plasmodium falciparum circumsporozoite protein-hepatitis B surface antigen subunit vaccine.]]>17115761585Gunasekaran, K., S.S. Sahu, K.N. Vijayakuma and P. Jambulingam,2009112149155Brown, G.V. and J.C. Reeder, 2002177230231Jeremiah, Z.A., E.K. Uko and E.A. Usanga,20088269274Kirby, M.J., C. Green, M.P. Milligan, C. Sismanidis and S. Chalarombos et al.,2008722Klayman, D.L.,198522810491055Le Roch, K.G., Y. Zhou, P.L. Blair, M. Grainger and J.K. Moch et al.,200330115031508Lindsay, S.W., P.M. Emerson and J.D. Charlwood,200218510514Mueller, M.S., I.B. Karhagomba, H.M. Hirt and E. Wemakor,2000Artemisia annua L. as a locally produced remedy for malaria in the tropics: Agricultural, chemical and clinical aspects.]]>73487493Muthaura, C.N., G.M. Rukunga, S.C. Chhabra, S.A. Omar and A.N. Guantai et al.,200721860867Ogoma, S.B., K. Kannady, S. Maggy, P.P. Chaki and N.J. Govella et al.,20098221221Opiyo, P., W.R. Mukabana, I. Kiche, E. Mathenge and F. Gerry et al.,200764848Osamor, V.C.,20094652664Osamor, V.C.,20092009Osamor, V.C., E. Adebiyi and S. Doumbia,20099378378Osamor, V., E. Adebiyi and S. Doumbia,20092009pp:491495Osamor, V.C.,20109196203Osamor, V.C.,20102096101Osamor, V.C., F.E. Adebiyi and S. Doumbia,2010Plasmodium falciparum genes to their functional roles using k-means.]]>2215225Osamor, V.C., O.S. Aloba and I.P. Osamor,2010107983Ralph, S.A., M.C. D'Ombrain and G.I. McFadden,20014145151Rasoanaivo, P., S. Ratsimamanga-Urverg, R. Milijaona, H. Rafatro and A. Rakoto-Ratsimamanga et al.,1994In vitro and in vivo chloroquine-potentiating action of Strychnos myrtoides alkaloids against chloroquine-resistant strains of Plasmodium malaria.]]>601316Snow, W.F.,19871921Trape, J.F., G. Pison, A. Speigel, C. Enel and C. Rogier,200218224230WHO,2005WHO/UNICEF,2003Wright, C.W.,200545561Wright, C.W. and D.C. Warhurst,20022002pp: 249-288pp: 249-288Wright, C.W., J.D. Phillipson, S.O. Awe, G.C. Kirby, D.C. Warhurst, J. Quetin-Leclercq and L. Angenot, 199610361363Yao-De, W., Z. Qi-Zhong and J. Jie-Sheng,1992Artemisia annua.]]>10290294Yeh, I., T. Hanekamp, S. Tsoka, P.D. Karp and R.B. Altman,2004Plasmodium falciparum metabolism: Organizing genomic information to facilitate drug discovery.]]>14917924WHO,2009