Journal of Biological Sciences1727-30481812-5719Asian Network for Scientific Information10.3923/jbs.2009.784.787Drupa margariticola]]>ChellaramC. JoneshS. AnandT. Prem EdwardJ.K.P. 7200997The aim of this study, the coral reef associated mollusc Drupa margariticola was screened for their insecticidal activity against a dreadful rice pest Sitophilus oryzae, The insecticidal activity of the crude and partially purified extracts of D. margariticola was tested using contact bioassay by the modified method. The extracts of acetone, ethyl acetate and dichloromethane caused 100% (10), 80.67% (8.67±1.25) and 80.0% (8±0.82) mortality respectively against S. oryzae at a concentration of 50 mg mL-1. The 100% acetone column purified fractions of extracts was found cause 100% at a concentration of 20 mg. The ED50 value of crude and column purified acetone extracts of D. margariticola was found to be lower 21.08 and 4.09 mg mL-1, respectively. The extract of D. margariticola screened for insecticidal activity clearly shows that the extract of acetone may possess some biologically active compounds. The exact route of entry is doubtful, which, in future can be cleared with studies on the mode of action of the extract tested.]]>Balogh, J.C. and J.L. Anderson,19921992pp: 221-354pp: 221-354Chellaram, C. and J.K.P. Edward,2009Drupa margariticola.]]>5236239Grode, S.H., T.R. James, J.H. Cardellina and K.D. Onan,1983Briareum polyanthes.]]>4852035207Broussalis, A.M., G.E. Ferraro, V.S. Martino, R. Pinzon, J.D. Coussio and J.C. Alvarez,199967219223Chellaram, C., K.M.E. Gnanambal and P. Jamila,2005Pteria chinensis.]]>2005pp: 173177Duke, S.O., J.J. Menn and J.R. Plimmer,19931993pp: 1-13pp: 1-13Finney, D.J.,19713rd Edn.,Gnanambal, K.M.E., C. Chellaram and J.K.P. Edward,2005Turbo intercostalis (Archaegastropoda: Turbnidae) and Cerithidea cingulata (Caenogastropoda: Potamiddidae).]]>2005pp: 132140Hubert, F., V.D.W. Knaap, T. Noel and P. Roch,1996Mytilus galloprovincialis, Ostrea edulis and Crassostrea gigas (bivalve, molluscs) haemolymph.]]>9115124Kernan, M.R. and D.J. Faulkner,1987Halichondria sp.]]>2828092812Dorow, E.,19931993pp: 7-8pp: 7-8Melnikov, N.N., 19711971pp: 197pp: 197Ware, G.W.,1982Watanabe, K., K. Umeda and M. Miyakado,1989Laurencia nipponica.]]>5325132515Wright, A.E.,19981998pp: 305-408pp: 305-408