Journal of Biological Sciences1727-30481812-5719Asian Network for Scientific Information10.3923/jbs.2009.746.752Pleurotus ostreatus) Against Glycerol-Induced Acute Renal Failure in Rats]]> SiragH.M. 7200997This study was undertaken to investigate the putative protective effect with antioxidant potential of the oyster mushroom (Pleurotus ostreatus) in glycerol-induced Acute Renal Failure (ARF) in rats. Four groups of rats were employed in this study, group I served as control, group II was given a single intramuscular dose of 50% glycerol in olive oil (8 mL kg-1 b.wt.), group III was given mushroom in the diet (62.5 g kg-1) and in drinking water (2.5 g L-1) for 3 weeks and group IV was given mushroom as the third group then was given a single intramuscular dose of 50% glycerol in the day 22 of mushroom administration. Oxidative stress markers in kidney, kidney abnormalities as well as hematological alteration were estimated. Glycerol treatment resulted in a marked renal oxidative stress, a significantly deranged renal function and a reduction in all hematological tested parameters. Pre-treatment with mushroom markedly reduced elevated thiobarbituric acid reacting substances, reduced glutathione, protein carbonyl and resorted the depleted renal antioxidant enzymes, attenuated renal dysfunction and the disturbances observed in hematological and biochemical parameters. These results suggest that Pleurotus ostreatus may have ability to protect the renal damage involved in acute renal failure in rats.]]>Abdel-moneim, A., E. El-zyat and O. Ahmed,1999287998Abdel-Moneim, A., O.M. Ahmed, S.M. Rawi and M. Zemmler,200134175206Aletor, V.A.,199554265268Allen, L. and E. Donald,19898419671973Amer, M. and S. Areida,2005Liv-Plus. A herbal formulation against hepatotoxicity induced by carbon tetrachloride and thioacetamide in male rats.]]>44199220Anand, C., V. Anand and R. Agarval,199634486488Grube, B.J., E.T. Eng, Y.C. Kao, A. Kwon and S. Chen,200113132883293Baliga, N., P. Walker and S. Shah,199629465477Belfield, A. and D. Goldberg,197112561574Better, O. and J. Stain,1990322825829Borchers, H.A., J.S. Stem, R.M. Hackman, C.L. Keen and M.E. Gershwin,1999221281293Dacie, J. and S. Lewis,19911991Devinder, S., C. Vikas and C. Kanwaljit,2004201143151Frankel, S., G. Robinson and M. Berenbaum,1998372731Gray, A. and P. Flatt,1998Agaricus compestris (Mushroom).]]>157259266Guerri, C. and S. Grisolia,1980126365384Gulcin, I., M. Oktay, E. Kirecci and O.I. Kufrevioglu,2003Pimpinella anisum L.) seed extracts.]]>83371382Hall, R.,20012001pp: 10001-1038pp: 10001-1038Halliwell, B. and J.M.C. Gutteridge,1990186185Halliwell, B.,1996163350Heather, M., W. David and J. Andrew,200413285290Henry, R.,1964pp: 181pp: 181Henry, R.,19742nd Edn.,pp: 525pp: 525Hokana ,Y. and J. Hokana,1981In vitro inhibition of platelet with low Dalton compounds from aques dialysates of edible fungi.]]>31177180Jayakumar, T., P. Thomas and P. Geraldine,2007Pleurotus ostreatus, on antioxidant of major organs of aged rats.]]>42183191Kattab, H., I. Abdallah and T. Saad,200313113Kim, H., T. Yokozawa, T. Nakagawa and S. Sasak,20044220092014Klivenyi, P., P. Andreassen and O. Aerrante,20002017Lin, S., P. Zhu and H. Liao,1998171515Lin, H.C.,19991999Manzi, P. and L. Pizzoferrato,200068315318Liu, F., V. Ooi and S. Chang,19976410051011Mattila, P., P. Salo-Vaananen, K. Konko, H. Aro and T. Jalava,20025064196422Moncada, S., R. Palmer and E. Higgs,199143109142Nishikimi, M., N.A. Rao and K. Yagi,197246849854Paller, M.,1988255539544Rawi, S., A. Abdel Moneim and O. Ahmed,199830211228Rikans, L.E. and K.R. Hornbrook,19971362116127Shah, S. and P. Walker,1988255F438F443Sheela, C.G. and K.T. Angusti,1995Allium sativum Linn. and gugulipid in cholesterol diet fed rats.]]>33337341Sies, H.,1985Singh, D., V. Chander and K. Chopra,2004201143151Snedecor, G. and W. Cochran,19897th Edn.,pp: 593pp: 593Stijve, T.,1977164201203Swanston-Flatt, S.K., C. Day, P.R. Flatt, B.J. Gould and C.Y. Bailey,1989106973Wasser, S.P. and A.L. Weis,199913162Yahuda, Z.,19934213228Yokozawa, T., H. Oura and I. Nishioka,199613143150Yoon, H., M. Moon, H. Pork and et al2008in vitro and in vivo.]]>46710715Zager, R. and L. Gamelin,1989256446455Zager, R.,199649314326Zettner, J. and A. Seligson,1964Dubrow, A. and W. Flamenbaum,19831983pp: 279-293pp: 279-293Dubrow, A. and W. Flamenbaum,19881988pp: 279-293pp: 279-293Hassan, H., W. El-Kholym and S. Nour, 2008352551Ravel, R.,19841984pp: 129-140pp: 129-140Nayana, J. and K.K. Janardhanan,2000Pleurotus florida.]]>79941943Antonia, M., M. Martinez-Tome, A.M. Jimenez, M. Vera Ana, M. Honrubia and P. Parras,20026516141622Hanasaki, Y., S. Ogawa and S. Fukui,199416845850Smith, C.D., J.M. Carney, P.E. Starke Reed, C.N. Oliver, E.R. Stadtman, R.A. Floyd and W.R. Markesbery,1991881054010543Ohkawa, H., N. Ohishi and K. Yagi,197995351358Patton, C.J. and S.R. Crouch,197749464469