Journal of Biological Sciences1727-30481812-5719Asian Network for Scientific Information10.3923/jbs.2007.648.652Zataria multiflora Boiss and Elaeagnus angustifolia on the Mouse Fetus Stomach]]>MalihezamanMonsefi MahbobeMokhberi Lahijani MaryamShams 4200774Zataria multiflora Boiss (ZmB) and Elaeagnus angustifolia (Ea) are used in traditional folk for stomach tonic. Many pregnant women take these plants to treat the digestive problem that is natural during pregnancy. There were no any reported about the effects of these plants in adult and fetus stomach. In order to investigated the probably effects of theses extracts on the fetus digestive system, 28 pregnant BALB/c mice were divided into control, Sham and experimental groups that treated with 200 mg kg•1 aqueous extract of ZmB and 640 mg kg•1 aqueous extract of Ea from 6th to 15th days of pregnancy. The sham group was gavaged with equal amount of distilled water while the control group did not have any treatment. Pregnant mice were sacrificed in 16th day of pregnancy and the fetuses were extracted and their Crown-Rump lengths and weights were measured. Seven fetuses from different mothers were selected and transverse serial sections of their stomach were prepared. The volumes of different layers of stomach were estimated by Cavalieri method. The epithelial and muscular cells of stomach were studied under transmission electron microscopy. There were no significant differences on the volume of stomach after treatment by ZmB but Ea increased the volume of different layers of stomach. No significant differences revealed for weight and CRL of the fetuses. The number of mitochondria of epithelial cells and RER in smooth muscle cells were increased in experimental groups. We concluded that these plants are nonpathogenic and safe and reinforcer for fetuses stomach.]]>Ahmadiani, A., J. Hosseiny, S. Semnanian, M. Javan, F. Saeedi, M. Kamalinejad and S. Saremi,2000Elaeagnus angustifolia fruit extract.]]>72287292Gurbuz, I., O. Austan, E. Yesilada, E. Sozik and O. Kutsal,2003889397Hosseinzadeh, H., M. Ramezani and G.A. Salmani,2000Zataria multiflora boiss extracts in mice and rats.]]>73379385Hosseinzadeh, H., M. Ramezani and N. Daneshmand,2001Elaeagnus angustifolia L. fruit seeds in mice.]]>72255262Hosseinzadeh, H., M. Ramezani and N. Namjo,2003Elaeagnus angustifolia L. fruit seeds in mice.]]>84275278Hunter, E.,19932nd Edn.,pp: 173pp: 173Lis-Balchin, M. and S. Hart,1997in vitro.]]>50185187Padmavathi, B., M. Upreti, V. Singh, A.R. Rao, R.P. Singh and P.C. Rath,2005515967Russ, J.C. and R.T. Dehoff,19992nd Edn.,Tabak, M., R. Armon, I. Potasman and I. Neeman,1996In vitro inhibition of Helicobacter pylori by extracts of thyme.]]>80667672Zargari, A.,19904th Edn.,pp: 1-57pp: 1-57