Journal of Applied Sciences1812-56541812-5662Asian Network for Scientific Information10.3923/jas.2015.999.1005NorhidayahAini VejayanJaya YusoffMashitah Mohamed 72015157Tongkat Ali is most famous for its aphrodisiac property and has gained reputation worldwide. Due to this, Tongkat Ali products are in demand and can be obtained in various forms. The quality of these products is not often authenticated. As Malaysia is one of the major producing countries of Tongkat Ali products, this study adapted a method which is used to determine the quality of Tongkat Ali products in the market. The quality of those products is based on the level of eurycomanone, the major compound in Tongkat Ali and the level should be around 0.8-1.5 w/v (%). A total of 41 products were obtained internationally and from Malaysia, with different pharmaceutical dosage, single or combined formulation. Those products were analyzed for eurycomanone content using HPLC, C18 column with acetonitrile and water as the mobile phase. The result indicated that 24 of the products contained eurycomanone. Eleven out of the 24 products complied (0.84-8.48% w/v) with the criteria set by Malaysian Standard and 9 of the products even have the eurycomanone level above (1.6-8.48% w/v) the set criteria. It was observed no eurycomanone was detected in some products even though the products have been registered with Malaysian herbal regulatory body, National Pharmaceutical Control Bureau (NPCB). In conclusion, this study suggests that the eurycomanone level should be utilized as a mandatory regulatory parameter for Tongkat Ali herbal preparation in the market besides the current parameters; microbial load and heavy metal contents alone.]]>Abdul Rahman, A.S., M.M.S. Yap, A.Y.M. Shakaff, M.N. Ahmad, Z. Dahari, Z. Ismail and M.S. Hitam,2004Eurycoma longifolia.]]>101191198Razak, M.F.A. and K.E. Aidoo,2011Eurycoma longifolia (Jack)-Based remedial products.]]>42327Ali, N., N.H. Hashim, B. Saad, K. Safan, M. Nakajima and T. Yoshizawa,20054317631772Ang, H.H. and M.K. Sim,1998Eurycoma longifolia increases sexual motivation in sexually naive male rats.]]>21779781Ang, H.H. and H.S. Cheang,2001Eurycoma longifolia Jack on laevator ani muscle in both uncastrated and testosterone-stimulated castrated intact male rats.]]>24437440Ang, H.H., K.L. Lee and M. Kiyoshi,2004Eurycoma longifolia Jack.]]>15303309Ang, H.H. and K.L. Lee,20064412451250Athimulam, A., S. Kumaresan, D.C.Y. Foo, M.R. Sarmidi and R.A. Aziz,2006Eurycoma longifolia water extract production.]]>84139149Bhat, R. and A.A. Karim,2010Eurycoma longifolia Jack): A review on its ethnobotany and pharmacological importance.]]>81669679Bogusz, M.J., H. Hassan, E. Al-Enazi, Z. Ibrahim and M. Al-Tufail,200641554564Hassan, N.H., R. Abdullah, L.S. Kiong, A.R. Ahmad and N. Abdullah et al.,20121168186825Low, B.S., P.K. Das and K.L. Chan,2013Eurycoma longifolia extract improved spermatogenesis and fertility in male rats via the hypothalamic-pituitary-gonadal axis.]]>145706714Malaysian Standard,2011Pages: 12Pages: 12Effendy, N.M., N. Mohamed, N. Muhammad, I.N. Mohamad aned A.N. Shuid,2012Eurycoma longifolia: Medicinal plant in the prevention and treatment of male osteoporosis due to androgen deficiency.]]>2012Mohd-Fuat, A.R., K.E. Aidoo, T.W. Calvert and A.A.G. Candlish,2006442331Islam, A.K.M.S., Z. Ismail, B. Saad, A.R. Othman, M.N. Ahmad and A.Y.M. Shakaf,2006Eurycoma longifolia extracts.]]>120245251Tambi, M.I. and M.K. Imran,2009Eurycoma longifolia jack in managing idiopathic male infertility.]]>2009pp: 165168Venhuis, B.J., J. Tan, M.J. Vredenbregt, X. Ge, M.Y. Low and D. de Kaste,2012214e20e22Wahab, N.A., M.M. Norfilza, W.N.H.A. Halim and S. Das,2010Eurycoma longifolia Jack on spermatogenesis in estrogen-treated rats.]]>659398Zanoli, P., M. Zavatti, C. Montanari and M. Baraldi,2009Eurycoma longifolia on the copulatory activity of sexually sluggish and impotent male rats.]]>126308313