Journal of Applied Sciences1812-56541812-5662Asian Network for Scientific Information10.3923/jas.2013.1473.1478BiKexin MaHuizi HuangPing 92013139A synergetic development between the informatization and the process innovation could enhance the competence of manufacturing enterprises and innovation capability effectively in the information era. A two-way relationship between the informatization and process innovation in manufacturing enterprises was studied in this research. In this study, the exploratory case study methodology was utilizedand data was collected from four manufacturing enterprises in China. The analysis explored how informatization influence the process innovation from four aspects including R and D informatization, production informatization, management informatization and business informatization; the impacts of process innovation on informatization were also analyzed from three aspects including process technology innovation, process equipment innovation and process management innovation. The discussion thus indicates a two-way interaction between the informatization and process innovation. The case study demonstrates that the informatization could influence the process innovation through different aspects. On the other hand, the influential effect of process innovation on the four aspects of informatization was partially proven as well. A two-way relationship model was also constructed based on the case analysis.]]>Awazu, Y., P. Baloh, K.C. Desouza, C.H. Wecht, J. Kim and S. Jha,2009525158Becker, W. and J. Dietz,200433209223Bi, K., H. Ma and P. Huang,201210138147Eisenhardt, K.M.,198914532550Fu, R. and K. Bi,2009302538Hatch, N.W. and D.C. Mowery,19984414611477Huai-Li, C., M. Deng-Zhe and F. Fei-Ya,200423541545Kaufmann, A. and F. Todtling,200130791804Loukis, E.N. and Y.K. Charalabidis,201364412420Nair, A. and M. Swink,200754742755Nambisan, S., J. Bacon and J. Throckmorton,2012554957OECD.,20053rd Edn.,Pages: 162Pages: 162Utterback, J.M. and W.J. Abernathy,19753639656Wang, L., G. Adamson, M. Holm and P. Moore,201231269279Xu, X.,2012287586Zhang, J.F., Z.J. Wu, P.F. Feng and D.W. Yu,20113889388948