Journal of Applied Sciences1812-56541812-5662Asian Network for Scientific Information10.3923/jas.2011.1062.1065MaftouniN. AmininasabM. KowsariF. 62011116Living cells have lipid bilayer membranes in liquid phase. The detail structure of nanobio membrane in biological cell membranes is illustrated here and the interfaces included in this structure are introduced. Molecular models of lipid bilayers have ignored the interface of two monolayers of nanobio membranes in detail by now, however in this paper a new physical model is proposed based on variation of surface tension in the interface of two monolayers of membrane. Experimental results have shown that some peptides and proteins like antimicrobial peptides and cytotoxins are able to change the shape of-or in some cases to destroy-the bilayer membrane during insertion to external monolayer. All interfaces in nanobio membrane are liquid/liquid type. Since in liquid/liquid interfaces the normal and tangential pressure components are very different near the interface, the usual Molecular Dynamics Simulation ensembles aren't suitable for this case. In this study appropriate ensembles to simulate liquid/liquid interfaces are presented with special focus on proper ones for surface tension analysis.]]>Lodish, H.F., A. Berk, J.E. Darnell, S.L. Zipursky, D. Baltimore and P. Matsudaira,20004th Edn.,Pages: 1084Pages: 1084Brogden, K.A.,20053238250Shanmugam, A., T. Bhuvaneswari, R.A. Nazeer, S. Sambasivam and S. Vairamani et al., 2008Babylonia spirata (L.).]]>3222229Hereman, T.C., J.D.T. Arruda-Neto, E. Cavalcante-Silva, T.E. Rodrigues, B. Buch, V. Arthur and M.C. Bittencourt-Oliveira,2007Microcystis panniformis Komarek et al. following treatments with gamma radiation and heating.]]>6604605Maftouni, N., A. Shahidian and M. Shariati,200715th Edn.,Maftouni, N., M. Amininasab and F. Kowsari,20092009Maftouni, N., M. Amininasab and F. Kowsari,2009Dubovskii, I.M., O.A. Olifirenko and V.V. Glupov,2005Galleria mellonella L. (Lepidoptera, Pyralidae) at peroral infestation by bacteria Bacillus thuringiensis ssp. galleriae.]]>412025Feofanov, A.V., G.V. Sharonov, M.V. Astapova, D.I. Rodionov, Y.N. Utkin and A.S. Arseniev,20053901118Perlmutter, J.D. and J.N. Sachs,2009178822842290Efremov, R.G., P.E. Volynsky, D.E. Nolde, P.V. Dubovskii and A.S. Arseniev,200283144153Mashl, R.J., H.L. Scott, S. Subramaniam and E. Jakobsson,20018130053015Zhang, Y. and S.E. Feller,1995103252266Andersen, H.C.,19807223842393Martyna, G.J., M.E. Tuckerman, D.J. Tobias and M.L. Klein,19968711171157Feller, S.E., Y. Zhang, R.W. Pastor and B.R. Brooks,199510346134621Parrinello, M. and A. Rahman,19815271827190Nose, S. and M.L. Klein,19835010551076Berendsen, H.J.C., J.P.M. Postma, W.F. Gunsteren, A. DiNola and J.R. Haak,19848136843689