Journal of Applied Sciences1812-56541812-5662Asian Network for Scientific Information10.3923/jas.2005.380.382ZiaaddiniHasan Mohammad Reza Ziaaddini 2200552To ascertain the prevalence of drug abuse among Iranian people a cross sectional household population based survey with census sampling was designed. The Roehampton questionnaire was used for evaluation. Opium abuse was the most frequent substance abuse (17.1%) and opioid dependency was 5.3%. Any one consumed alcohol. Only 4 person had daily use of cannabis, 3 person had daily use of heroin and 8 person had daily abuse of tranquilizers. The most common usage method was inhalation and there was no injection. There was a statistical significant difference between sex and substance abuse. In Iran like other countries drug abuse in male is more frequent than female. The most common substance abuse is opium, it should be noted that in Iran, it is very difficult to obtain LSD, cocaine, or psychedelics, specially, in rural area. Cultural attitude toward substance use quite likely affect the types and patterns of use.]]>Ghodse, H.,1995233131Ghodse, H.,1999175310312Moharreri, M.R.,1979283139Zarabi, A.,198038188Ahmadi, J., H. Arabi and Y. Mansouri,200328591595Ahmadi, J., N. Maharlooy and M. Alishahi,2004136064Dalvand, S., C. Agahi and C. Spencer,1984148792Ahmadi, J. and M. Hasani,200328375379Spencer, C.,1985171924Maddux, J.F., S.K. Hoppe, R.M. Costello,1986143187191Mott, J. and C.M. Black,19951st Edn.,Johnson, L.D., P.M. O'Malley and J.G. Bachman,19911st Edn.,Anonymous,19971997