Journal of Applied Sciences1812-56541812-5662Asian Network for Scientific Information10.3923/jas.2005.1655.1657AminiM. Kh. Abdi M. Darabi A. Shafiee 9200559A simple, sensitive isocratic method for detection and quantification of ofloxacin in plasma has been developed. The assay consisted of reversed HPLC with UV detection. Separation was achieved on a C18 column. The detection limit was 10 ng mL1 in plasma. The validation data has been studied. This method provides sufficient sensitivity for pharmacokinetic studies and dose control in veterinary as well as in human medicine.]]>Gaur, A., S. Sani, S. Garg, R.K. Chaudhary and A.K. Srivasta,200427115117Herbert, D., C.N. Paramas, K. Venkatesan, G. Kubendiran, R. Prabhakar and D.A. Mitchison,1996Mycobacterium tuberculosis.]]>4022962304Brown, S.A.,199619114Chandra, I. and K. Hemanth,20017609195Coguic, A., L.E.R. Bidault, R. Farinotti and A. Dauphin,1988434320323Jehl, F., C. Gallion and H. Monteil,1990531509548Teja-Isvadharm, P., D. Keeratatithakul, G. Watt, H.K. Webster and M.D. Edstien,199113263267Mignot, A. and M.A. Lefebvre,1988430192197Katagiri, Y., K. Naora, N. Ichikawa, M. Hyashibara and K. Iwamaoto,1988431135142Lehr, K.H. and P. Damm,1988425153158Greene, C.E. and S.C. Budsberg,19931993pp: 473-484pp: 473-484