International Journal of Zoological Research1811-97781811-9786Academic Journals Inc.10.3923/ijzr.2020.1.11Sargassum sp.) Extract to Prevent Vibriosis in White Shrimp (Litopenaeus vannamei) Juvenile]]>Mulyadi NurIndriyani IbaWa 12020161Background and Objectives: Marine algae, especially brown algae (Sargassum sp.), is a natural compound plant capable of being prophylactic and immunostimulant. This study was aimed to evaluate the efficacy of seaweed (Sargassum sp.) extract to improve resistance and immune response of juvenile white shrimps (Litopenaeus vannamei) infected by Vibrio algynolyticus. Materials and Methods: The ethanolic extract of seaweed was used to evaluate its antibacterial effect by immerse the juvenile shrimp at a dose level of 0 (control), 150, 250 and 350 ppm for 3 h. Shrimp immune response was observed based on total haemocyte count (THC) and differential haemocyte count (DHC). Moreover, the bacterial challenge test was used for the evaluation of shrimp resistance. 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