International Journal of Poultry Science1682-83561994-7992Asian Network for Scientific Information10.3923/ijps.2011.670.676FeriaC.A. Ruiz- LarrisonE. DavisM. FarnellM. CareyJ. GrimesJ.L. PittsJ. 92011109The effects of Sodium Bisulfate (SB) supplementation on growth, intestinal integrity, blood gas chemistry and litter microbiology of broiler chickens were evaluated. Birds were fed a corn-soybean meal diet meeting all of the NRC (1994) requirements. In Exp. 1 birds were fed diets supplemented with 0 (control diet, CTL), 0.25, 0.5, or 0.75% (w/w) of feed-grade SB (SB25, SB50 and SB75, respectively); in Exp. 2 and 3 only the CTL, SB25 and SB75 diets were evaluated. In Exp. 4 the chicks (n = 920) were placed in 20 pens and fed the CTL diet, or the SB25 diet offered during the first 21, 35, or 49 d (21D, 35D and 49D, respectively); the CTL diet was offered until the end of experiment (d 49) for treatments 21D and 35D. The data was analyzed as a two way ANOVA (diet and gender as main effects). In Exp. 1 birds fed diets with SB had lower FC than birds fed the CTL diet, but BW was not different among treatments. In Exp. 2 females fed the SB25 diet were heavier (p<0.05) at d 21 than females fed the CTL or the SB75 diet; the FC was similar among groups. In Exp. 3 chickens fed the SB25 or SB75 diets were consistently heavier and had a lower FC (p<0.05) than birds fed the CTL diet. In Exp. 4 birds fed the SB25 diet had lower BW than birds fed the CTL diet; however birds in the 35D or 49D treatments had a better FC than birds fed the CTL diet. The litter of birds fed the SB25 diet had lower levels of Salmonella at wk 4 and 6 in Experiment 3 and at wk 4 in Exp. 4. Neither the duodenum villus height nor the blood gas composition was affected by the dietary treatments. Our results show that SB supplementation improves productive performance and reduces the environmental levels of Salmonella, with variable efficacy, perhaps due to seasonal conditions.]]>Adil, S., T. Banday, G.A. Bhat, M.S. Mir and M. Rehman,20102010Ahmad, T., T. Khalid, T. Mushtaq, M.A. Mirza, A. Nadeem, M.E. Babar and G. Ahmad,20088712761280Arad, Z. and J. Marder,1983Gallus domesticus): Comparison between breeds.]]>74125130Baurhoo, B., L. Phillip and C.A. Ruiz-Feria,20078610701078Borges, S.A., A.V.F. da Silva, A. Majork, D.M. Hooge and K.R. Cummings,20048315511558Borges, S.A., A.V.F. da Silva, J. Ariki, D.M. Hooge and K.R. Cummings,200382428435Cherrington, C.A., M. Hinton and I. Chopra,1990Escherichia coli.]]>686974Corrier, D.E., D.J. Nisbet, A.G. Hollister, C.M. Scanlan, B.M. Hargis and J.R. Deloach,19937211641168Fernandez-Rubio, C., C. Ordonez, J. Abad-Gonzalez, A. Garcia-Gallego, M.P. Honrubia, J.J. Mallo and R. Balana-Fouce,2009Salmonella Enteritidis infection.]]>88943948Heres, L., B. Engel, H.A. Urlings, J.A. Wagenaar and F. van Knapen,2004Campylobacter and Salmonella.]]>99259267Hernandez, F., V. Garcia, J. Madrid, J. Orengo, P. Catala and M.D. Megias,2006475056Line, J.E.,2002Campylobacter and Salmonella populations associated with chickens raised on acidified litter.]]>8114731477Monreal, G. and G. Paul,1989102405409NRC.,19949th Edn.,Pages: 176Pages: 176Phillips, I., M. Casewell, T. Cox, B. de Groot and C. Friis et al.,2004532852Ricke, S.C.,200382632639Senkoylu, N., H.E. Samli, M. Kanter and A. Agma,200755479490Van Immerseel, F., F. Boyen, I. Gantois, L. Timbermont and L. Bohez et al.,2005Salmonella in poultry.]]>8418511856Van der Zijpp, A.J.,198339118131Wales, A.D., V.M. Allen and R.H. Davies,2010Salmonella.]]>7315Whittow, G.C., P.D. Sturkie and G. Stein Jr.,19667296301