International Journal of Pharmacology1811-77751812-5700Asian Network for Scientific Information10.3923/ijp.2017.1103.1114BadrAhmed Noah ShehataMohamed Gamal Abdel-RazekAdel Gabr 82017138Background and Objective: Jojoba as well as jatropha contains many active ingredients that have important roles to give them antioxidant efficiency, furthermore; fatty acids composition give a substantial function as antimicrobial properties. Thus, it may enhance the resistance to pathogenic microbes and toxins. This study aimed to evaluate antioxidant, antimicrobial and antifungal activities of jojoba and jatropha materials. Materials and Methods: Jojoba and jatropha oils fatty acid composition were analyzed, total phenolic and flavonoid was determined and the antioxidant activities were evaluated. The antimicrobial activity of extracts was investigated against some pathogens by agar well and disk diffusion method. The oil and pomace extract of jojoba and jatropha were tested for antifungal activities against four toxigenic fungi. Inhibitory activity of materials against aflatoxins production was evaluated using High-performance liquid chromatography (HPLC). Statically analysis using one way ANOVA was done using SPSS v.16. Results: The major fatty acids were mono-unsaturated fatty acids, 97.4% for jojoba and 42.2% for jatropha, while palmitic acid and stearic acid being the major saturated fatty acids in jatropha oil. Total phenolic and flavonoid contents were ranged from 12.5-996.5 mg of GAE g1 and 5.92-180.83 mg of catechol g1, respectively. Reducing ratio of aflatoxins were vary between 43.8-26.6% for aflatoxin B1, 38.61-14.5% for aflatoxin B2, 33.2-14.6% for aflatoxin G1 and 34.3-9.4% for aflatoxin G2, while for total aflatoxins were between 38.7-18.75%. Conclusion: Jojoba oil was more effective and more antimicrobial than jatropha oil, the pomace extract shows more efficacy for jatropha than jojoba and they have variable effect against pathogens and aflatoxins.]]>Paterson, R.R.M. and N. Lima,20104319021914Medina, A., A. Rodriguez and N. Magan,2014Aspergillus flavus and aflatoxin B1 production.]]>2014Sabry, B.A., A.S. Hathout, A. Nooh, S.E. Aly and M.G. Shehata,2016Aspergillus parasiticus in Egyptian sesame seeds.]]>9308319Badr, A.N., S.M. Abdel-Fatah, Y.H. Abu Sree and H.A. Amra,201711110Badr, A.N., F.L. Antonio, A.A. Hassan and H. Taha,201710178185McKeon, T.A., W. Serson, M. Al-Amery, S. Patel and T. Phillips et al.,20162016pp: 275-341.pp: 275-341.Yang, J., J. Li, Y. Jiang, X. Duan and H. Qu et al.,2014546483Jahanshiri, Z., M. Shams-Ghahfarokhi, A. Allameh and M. Razzaghi-Abyaneh,2015Aspergillus parasiticus by downregulating the expression of major genes in the toxin biosynthetic pathway.]]>3110711078Badr, A.N., N. Fatma, M.G. Shehata and H.A. Amra,201717184195Nooh, A., H. Amra, M.M. Youssef and A.A. El-Banna,20142521532Richter, E., E. Roller, U. Kunkel, T.A. Ternes and A. Coors,2016208512522Lafka, T.I., A.E. Lazou, V.J. Sinanoglou and E.S. Lazos,20111259298Alves, S.P. and R.J.B. Bessa,2009121651305139Dewanto, V., X. Wu, K.K. Adom and R.H. Liu,20025030103014Sakanaka, S., Y. Tachibana and Y. Okada,200589569575Shimada, K., K. Fujikawa, K. Yahara and T. Nakamura,199240945948Re, R., N. Pellegrini, A. Proteggente, A. Pannala, M. Yang and C. Rice-Evans,19992612311237NCCLS.,19976th Edn.,Ferraro, M.J.,20005th Edn.,Pages: 36Pages: 36Schlumbaum, A., F. Mauch, U. Vogeli and T. Boller,1986324365367Akoh, C.C.,20174th Edn.,Pages: 1029Pages: 1029Pastor-Cavada, E., R. Juan, J.E. Pastor, M. Alaiza and J. Vioque,2009Lathyrus species from South Spain.]]>42705709Prior, R.L., X. Wu and K. Schaich,20055342904302Umamaheswari, M. and T.K. Chatterjee,2008In vitro antioxidant activities of the fractions of Coccinia grandis L. leaf extract.]]>56173Barbaro, B., G. Toietta, R. Maggio, M. Arciello, M. Tarocchi, A. Galli and C. Balsano,2014151850818524Chan, E.W.C., L.Q. Kong, K.Y. Yee, W.Y. Chua and T.Y. Loo,20121142151Calder, P.C., R. Albers, J.M. Antoine, S. Blum and R. Bourdet-Sicard et al.,2009101145Devasagayam, T.P.A., J.C. Tilak, K.K. Boloor, K.S. Sane, S.S. Ghaskadbi and R.D. Lele,200452794804Carraro, L., L. Fasolato, F. Montemurro, M.E. Martino and S. Balzan et al.,2014Escherichia coli K-12]]>7265275Silva, S., E.M. Costa, M.R. Costa, M.F. Pereira, J.O. Pereira, J.C. Soares and M.M. Pintado,2015Vaccinium corymbosum as inhibitors of Staphylococcus aureus.]]>51314320Mujumdar, A.M. and A.V. Misar,2004Jatropha curcas roots in mice and rats.]]>901115Ravindranath, N., M.R. Reddy, C. Ramesh, R. Ramu, A. Prabhakar, B. Jagadeesh and and B. Das,2004Jatropha curcas.]]>52608611Thomas, R., N.K. Sah and P.B. Sharma,2008Jatropha curcas: A mini review.]]>9315324Abdel-Wahhab, M.A., O. Joubert, A.A. El-Nekeety, H.A. Sharaf, F.M. Abu-Salem and B.H. Rihn,201627886