International Journal of Pharmacology1811-77751812-5700Asian Network for Scientific Information10.3923/ijp.2015.542.551Nephelium lappaceum Rind Extract in High Fat-Induced Diabetic Rats]]>SubramaniamShonia RadhakrishnanAmmu ChakravarthiSrikumar PalanisamyUma Devi HaleagraharaNagaraja 62015116This study investigated the antidiabetic effects of the rind of Nephelium lappaceum extract in a high fat-induced diabetic rat model. Ethanolic N. lappaceum rind extract was prepared and standardised with geraniin using high performance liquid chromatography. Male Sprague Dawley rats were fed on a high fat diet followed by 210 mg kg1 nicotinamide and 55 mg kg1 streptozotocin injection to induce type 2 diabetes. The diabetic rats were treated with N. lappaceum rind at concentrations of 500 and 2000 mg for 28 days. Positive control rats were treated with 200 mg metformin. 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