International Journal of Pharmacology1811-77751812-5700Asian Network for Scientific Information10.3923/ijp.2012.204.208Melissa officinalis L., Cinnamomum zeylanicum and Urtica dioica on Hepatic Enzymes Activity in Patients with Nonalcoholic Fatty Liver Disease]]>MalekiradAli Akbar MojtabaeeMohadeseh FaghihMahya VaeziGholamhassan AbdollahiMohammad 3201283Non-alcoholic fatty liver disease (NAFLD) is becoming one of the most common causes of chronic liver disease worldwide that does not have obvious effective drug. The aim of this study was to determine the capability of Melissa officinalis L. (Lemon balm), Cinnamomum zeylanicum and Urtica dioica mixture infusion (1.5, 0.5 and 0.25 g/100 mL) on patients with NAFLD. The study was designed as a before-after clinical trial and performed on 35 patients with NAFLD. They were asked to drink the mixture infusion which were prepared in special bags twice a day for 30 days. Liver markers of NAFLD such as alanine amino transferase (ALT), aspartate amino transferase (AST) and alkaline phosphates (ALKp) in plasma were measured before and after using the infusion. The use of the infusion in NAFLD resulted in a significant decrease in ALT. Also activity of the AST and ALP were decreased after administration of the infusion but these decreases were not significant. Also a significant decrease in grade of sonographic examination was found. A significant linear correlation was also found between age and AST and ALT. However, no linear correlation was found between gender and weight and liver enzymes. Taken altogether, it is concluded that consumption of the present mixture has some benefits in NAFLD.]]>Abdollahi, M., A. Ranjbar, S. Shadnia, S. Nikfar and A. Rezaie,200410RA141RA147Adams, L.A. and P. Angulo,200682315322Amin, K.A. and T.M. Abd El-Twab,20092254265Bolkent, S., R. Yanardag, O. Karabulut-Bulan and B. Yesilyaprak,2005Melissa officinalis L. extract on liver of hyperlipidemic rats: A morphological and biochemical study.]]>99391398Bugianesi, E., E. Gentilcore, R. Manini, S. Natale and E. Vanni et al.,200510010821090Clark, J.M.,200640S5S10Fani, A., AA. Malekirad, I. Fani, H. Allahnazem and K. Rahzani et al.,2008Cinnamomum zeylanicum for radiology unit staff.]]>8384389Golalipour, M.J., S. Ghafari and M.H. Farsi,2009Urtica dioica L. extract on quantitative morphometric alterations of liver parenchymal cells in STZ diabetic rats.]]>2713391344Grattagliano, I., P. Portincasa, V.O. Palmieri and G. Palasciano,200753857863Hasani-Ranjbar, S., H. Vahidi, S. Taslimi, N. Karimi, B. Larijani and M. Abdollahi,20106691695Hasani-Ranjbar, S., N. Nayebi, B. Larijani and M. Abdollahi,2010Teucrium species; from anti-oxidant to anti-diabetic effects.]]>6315325Kandis, H., S. Karapolat, U. Yildirim, A. Saritas, S. Gezer and R. Memisogullari,2010Urtica dioica on hepatic ischemia-reperfusion injury in rats.]]>6513571361Lavine, J.E., J.B. Schwimmer, M.L. van Natta, J.P. Molleston and K.F. Murray et al.,201130516591668Malekirad, A.A., N. Hosseini, M. Bayrami, T. Hashemi, K. Rahzani and M. Abdollahi,20116953957Mehta, K., D.H. van Thiel, N. Shah and S. Mobarhan,200260289293Mohseni-Salehi-Monfared, S.S., H. Vahidi, A.H. Abdolghaffari, S. Nikfar and M. Abdollahi,20091544814490Moselhy, S.S. and H.K. Ali,2009429398Moselhy, S.S. and H.H. Junbi,20101151155Ozkol, H., D. Musa, Y. Tuluce and I. Koyuncu,2011Urtica dioica L against cisplatin-induced toxicity in mice bearing ehrlich ascites carcinoma.]]>2011Park, S.H.,2008141227Raszeja-Wyszomirska, J., M. Lawniczak, W. Marlicz, J. Miezynska-Kurtycz and P. Milkiewicz,200824568571Rahimi, H.R., M. Gholami, H.R. Khorram-Khorshid, F. Gharibdoost and M. Abdollahi,201273845Rahimi, R., S. Nikfar, B. Larijani and M. Abdollahi,200559365373Rahimi, R., S. Nikfar, A. Rezaie and M. Abdollahi,200928417434Ranjbar, A., S. Ghaseminejhad, H. Takalu, A. Baiaty, F. Rahimi and M. Abdollahi,2007Cinnamomum zeylanicum) in operating room personnel; a before/after cross sectional clinical trial.]]>3482486Rezaie, A., R.D. Parker and M. Abdollahi,20075220152021Rodriguez, G., S. Gallego, C. Breidenassel, L.A. Moreno and F. Gottrand,201025712717Sharif, P.S, M. Asalforoush, F. Ameri, B. Larijani and M. Abdollahi,201032179186Smith, B.W. and L.A. Adams,20114897113Stein, L.L., M.H. Dong and R. Loomba,200926893907Mehri, A., S. Hasani-Ranjbar, B. Larijani and M. Abdollahi,2011Urtica dioica in the treatment of diabetes.]]>7161170Momtaz, S. and M. Abdollahi,2010Satureja species; From antioxidant, antimicrobial, antidiabetes and anti-hyperlipidemic to reproductive stimulation.]]>6346353Zeraatpishe, A., S. Oryan, M.H. Bagheri, A.A. Pilevarian, A.A. Malekirad, M. Baeeri and M. Abdollahi,2011Melissa officinalis L. on oxidative status and DNA damage in subjects exposed to long-term low-dose ionizing radiation.]]>7205212Monfared, S.S.M.S., B. Larijani and M. Abdollahi,20091511531161