International Journal of Pharmacology1811-77751812-5700Asian Network for Scientific Information10.3923/ijp.2010.425.430Rosmarinus officinalis Freeze-Dried Extract]]>EmanuelV. AdrianV. SultanaNita 4201064The aim of this study was to obtain a freeze-dried extract with an important antioxidant and antimicrobial effect from Rosmarinus officinalis. The extracts were obtained in a fluidized bed solid extractor and there has resulted that the optimal values of phenols, flavonoids and the highest reduction power were determined when using 70% ethanol as solvent, the antioxidant activity ranging between 90-95%. In case of the freeze-dried product, the maximum antioxidant activity was registered when using 0.2 mg mL-1 powder and the results were optimal as well in case of determining flavonoids, phenols and the reduction power. The antimicrobial effect of the extracts and of the freeze-dried product were quantified by using the Colony Quant software on the strains Escherichia coli CBAB 2, Bacillus cereus CMGB 215, Listeria innocua CMGB 218. An inhibition area of maximum 2 cm resulted when using 70% ethanol as solvent. The optimal inhibitory effect of the freeze-dried product, of around 1.8 cm, was determined by a 0.2 mg mL-1 concentration.]]>Afolayan, A.J., O.M. Aboyade and M.O. Sofidiya,2008Malva parviflora L. (Malvaceae).]]>8945949Afolayan, A.J. and F.O. Jimoh,20095424431Caruso, J.L., J. Callahan, C. de Chant, K. Jayasimhulu and G.D. Winget,2000Rosmarinus officinalis.]]>19500503Bjelakovic, G., D. Nikolova, L.L. Gluud, R.G. Simonetti and C. Gluud,200827176Carvalho, R.N., S.M. Lucinewton, P.T.V. Rosa and M.A.A. Meireles,2005Rosmarinus officinalis): Kinetic data, extract's global yield, composition and antioxidant activity.]]>35197204Charles, L.C., L.R. Steven, M.N. Gillian, K.S. Brad and T.B. David,2005Rosmarinus officinalis.]]>6898100Colin, D.K. and J.H. Bruce,20035452458Jazani, N.H., M. Zartoshti and S. Shahabi,2008Cuminum cyminum essential oil on burn isolates of Pseudomonas aeruginosa.]]>4157159Knight, J.A.,200030145158Krishna, K.L., K. Mruthunjaya and J.A. Patel,2010Justicia gendarussa burm.]]>67280Oguntibeju, O.O., A.J. Esterhuyse and E.J. Truter,2009831073117Puangpronpitag, D., N. Niamsa and C. Sittiwet,2009Eugenia caryophyllum bullock and harrison) aqueous extract against food-borne pathogen bacteria.]]>5281284Rahman, A., M.M. Rahman, M.I. Sheik, S.M. Shadli and M.F. Alam,2008Cassia sophera L.]]>715911593Rozman, T. and B. Jersek,2009Rosmarinus officinalis L.) against different species of Listeria.]]>935158Blomhoff, R.,2005164754Miresmailli, S., R. Bradbury and M.B. Isman,2006Rosmarinus officinalis L. essential oil and blends of its major constituents against Tetranychus urticae Koch (Acari: Tetranychidae) on two different host plants.]]>62366371Sang, U.P., M.R. Uddin, H. Xu, Y.K. Kim and Y.L. Sook,2008749594965Scartezzini, P. and E. Speroni,2000712343Satoh, T., K. Kosaka, K. Itoh, A. Kobayashi and M. Yamamoto et al.,2008in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1.]]>10411161131Szabo, M.R., C. Iditoiu, D. Chambre and A.X. Lupea,200761214216Stuckey, B.N. and C.E. Osborne,200743228232Takahashi, T., T. Tabuchi, Y. Tamaki, K. Kosaka, Y. Takikawa and T. Satoh,20098549554