International Journal of Pharmacology1811-77751812-5700Asian Network for Scientific Information10.3923/ijp.2010.311.314Pandanus odoratissimus Extract]]>LondonkarRamesh KambleAbhaykumar ReddyV. Chinnappa 3201063This study examined the anti-inflammatory activity of Pandanus odoratissimus. Anti-inflammatory drugs presently available for the treatment of various inflammatory disorders have diverse and undesirable side effects. In recent years, many active chemicals have been isolated from plants possessing anti-inflammatory activity. The anti-inflammatory activity was estimated by carrageenan-induced acute and formalin-induced chronic paw edema models in rats. The methanolic extract of Pandanus odoratissimus was given in the doses of 25, 50 and100 mg kg -1. The plant extract at the dose of 100 mg kg -1 showed significant anti-inflammatory activity peaked at 3 h where, it caused inhibition for the increase in carrageenan-induced acute (68%) and for the increase in formalin-induced chronic (64.2%) paw edema models in rats. The standard drug was used as diclofenac sodium. As a result methanolic extract of Pandanus odoratissimus was shown to have an anti-inflammatory activity.]]>Khan, M.N., J.S. Choi, M.C. Lee, E. Kim, T.J. Nam, H. Fujii and Y.K. Hong,200829465469Dinarello, C.A.,200683447S455SKida, Y., M. Kobayashi, T. Suzuki, A. Takeshita, Y. Okamatsu and S. Hanazawa,200529159168Chrubasik, J.E., B.D. Roufogalis and S. Chrubasik,200721675683Naesdal, J. and K. Brown,200629119132Rasadah, M.A., A.A. Khozirah, A.A. Aznie and M.M. Nik,2004Sandoricum koetjape merr.]]>11261263Berenblum, I.,1941Cocarcinogenic action of corton resin.]]>14448Subbaramaiah, K., D. Zakin, B.B. Welkaler and J.A. Dannenberg,1997216201210Londonkar, R. and A. Kamble,2009Pandanus odoratissimus.]]>5377380Lakshmi, B., T.A. Ajith, N. Sheena, N. Gunapalan and K.K. Janardhanan,2002Antiperoxidative, Anti-inflammatory and Antimutagenic activities of ethanol extract of the mycelium of Ganoderma lucidum occurring in south India.]]>18597Kirtikar, K.R. and B.D. Basu,2000Vol. 10,pp: 3565pp: 3565Ajith, T.A. and K.K. Janardhanan,2001Phellinus rimosus (Berk) Pilat.]]>3911661169