International Journal of Pharmacology1811-77751812-5700Asian Network for Scientific Information10.3923/ijp.2008.51.55Hippocratea africana]]>OkokonJude E. AntiaBassey S. UmohEmem 1200841The ethanolic root extract of Hippocratea africana
(200-600 mg kg-1) was evaluated for analgesic, anti-inflammatory
and antipyretic properties. The extract dose dependently inhibited acetic
acid-induced writhing, formalin-induced paw licking and thermally -induced
pain in mice. The extract also inhibited fresh egg albumin, carrageenin
and xylene-induced inflammation in mice. These inhibitions were statistically
significant (p<0.05) when compared to control. The roots extracts was
also found to reduce pyrexia in rats. The analgesic, anti-inflammatory
and antipyretic activities of the extract may be related to its active
constituents such as tannins, saponins, steroid and flavonoids.]]>Akah, P.A. and A.I. Nwambie,199442179182Amico-Roxas, M., A. Caruso, S. Trombadore, R. Scifo and U. Scapagnini,1984272103117Besra, S.E., R.M. Sharma and A. Gomes,1996Litchi chinensis Gaertn. (Sapindaceae).]]>5416Correa, C.R. and J.B. Calixto,19931 and B2 kinin receptors in formalin-induced nociceptive response in the mouse.]]>110193198Correa, C.R., D.J. Kyle, S. Chakravarty and J.B. Calixto,19962 bradykinin receptor antagonist NPC 18688 in mice.]]>117552558Dalziel, J.M.,19561956Ekpendu, T.O., P.A. Akah, A.A. Adesomoju and J.I. Okogun,1994Mitracarpus scaber extracts.]]>32191195Gorski, E., C.R. Correa, V.C. Filhe, R.A. Yunes and J.B. Calixto,1993Phyllanthus corcovadensis.]]>4510461049Gural, M.L., P.P. Kohli and P.H. Sexena,195568992Hess, S.M. and R.C. Milonig,19721972Hunskaar, S. and K. Hole,198730103114Lin, L.L., A.Y. Lin and J.L. Knopt,19922 is coupled to hormonally regulated release of arachidonic acid.]]>8961476157Ogbole, O.O., M.N. Ekor, B.B. Oluremi, A.A. Ajaiyeoba, A.A. Gbolade, M.A. Ayoola and A.A. Adeyemi,2007Hippocratea indica root bark and Poga oleosa fruits.]]>4372376Okokon, J.E., B.N. Ita and A.E. Udokpoh,2006in vivo antimalarial activities of Uvariae chamae and Hippocratea africana.]]>100585590Parmer, N.S. and M.N. Ghosh,1978Hibiscus vitifolicus Linn.]]>10277293Perez, R.M., S. Perez, M.A. Zavala and M. Salazar,1995Hippocratea excelsa.]]>478590Santos, A.R.S., F.V. Cechinel, R. Niero, A.M. Viana, F.N. Moreno, M.M. Campos, R.A. Yunes and J.B. Calixto,1994Phillanthus.]]>46755759Tjolsen, A., O.G. Berge, S. Hunskaar, J.H. Rosland and K. Hole,199251517Vane, T. and R. Booting,198718996Vaz, Z.R., V.C. Filho, R.A. Yunes and J.B. Calixto,1996278304312Vaz, Z.R., E.A. Risley and J.B. Calixto,199711101106Winter, C.A., E.A. Risley and G.W. Nuss,1962111544547