International Journal of Pharmacology1811-77751812-5700Asian Network for Scientific Information10.3923/ijp.2008.46.50HosseiniSeyed Nejat MousavinasabSeyed Nouraddin ShoghliAlireza RahmanpourHaleh 1200841The aim of this study was to compare the outcome of Xenoderm (biologic
dressing) and `conventional` treatments (Silver sulfadiazine) in pediatrics`
burns in our burn center, which is the only burn center in Zanjan province.
In this non-randomized clinical trial, 86 burned pediatrics were investigated.
The patients were divided into two groups. Those in the `conventional`
group (n = 35) did not accepted to enter in Xenoderm group and the second
group (n = 51) accepted to enter in to Xenoderm group. Mortality rates
in the `conventional` group were 5 (14.3%) and no death were in the Xenoderm
group. The median of number of dressing in the `conventional` group and
Xenoderm group were 10 and 3 (p = 0.0005), respectively. In 20 to 39%
Total Body Surface Area (TBSA), the median of first admission hospital
stay in the `conventional` group and Xenoderm group were 20 and 7.5 (p
= 0.001), respectively. In conclusion, the results indicate that Xenoderm
dressings offer a lower mortality, hospital stay and dressing exchange
in pediatrics burns. A randomized clinical trial that compares the number
of operations, albumin intake and scar formation in pediatric burns is
warranted.]]>Albertyn, R., S.W. Bickler and H. Rode,200632605612Barret, J.P., P. Dziewulski, P.I. Ramzy, S.E. Wolf, M.H. Desai and D.N. Herndon,20001056265Becker, D.,199810171175Brunicardi, F.C., D.K. Andersen, T.R. Billiar, D.L. Dunn, J.G. Hunter and R.E. Pollock,20058th Edn.pp: 189-221pp: 189-221Burleson, R. and B. Eiseman,197272315322Chiu, T. and M. Shah,200228279282Chiu, T. and A. Burd,200523419423Costagliola, M. and M. Agorsi,20052112351240Davy, R.B.,1999256268Elliot, R.A. and J.G. Hoehn,197352401405Erickson, E.J., S.W. Merrell, J.R. Saffle and J.J. Sullivan,199126821825Goldman, S., L. Aharonson-Daniel and K. Peleg,200632467472Ho, W.S. and S.Y. Ying,200127119123Hosseini, S.N., S.N. Mousavinasab and M. Fallahnezha,200733776781Kiene, S., H. Schill, J. Roewer and U. Frick,197610114811494Klein, L., P. Mericka and J. Preis,19951995pp: 337-345pp: 337-345Kumar, P., P.T. Chirayil and R. Chittoria,200026261264Kumar, R.J., R.M. Kimble, R. Boots and S.P. Pegg,200474622626Lukish, J.R., M.R. Eichelberger, K.D. Newman, M. Pao and K. Nobuhara et al.,20013611181121Maghsoudi, H. and N. Samnia,200531721725May, S.R.,19918243249Paddock, H.N., R. Fabia, S. Giles, J. Hayes, W. Lowell, D. Adams and G.E. Besner,200742211213Potokar, T.,200531401401Pruitt, B.A. and N.S. Levine,1984119312322Rawlins, J.M., A.A. Khan, A.F. Shenton and D.T. Sharpe,200723289293Schmitt, W.,197398320324Townsend, C.M., R.D. Beuchamp, B.M. Evers and K.L. Mattox,200417th Edn.pp: 580-585pp: 580-585Xin, W., Z. Yin, Z. Qin, L. Jian, P. Tanuseputro, M. Gomez, M. Beveridge and L. Zhenjiang,20062613618