International Journal of Pharmacology1811-77751812-5700Asian Network for Scientific Information10.3923/ijp.2007.201.203RahmanpoorHaleh HosseiniSeyed NejatMousavinasabSeyed NouraddinTadayonParvin KarimiFatemeh 2200732Pain relief of good quality after Cesarean Section (CS) results in early mobilization and good early mother-child interaction. Usually Narcotics are using for analgesia after CS pain have side effects like sedation, nausea, ileus and respiratory depression. The object of this study is the comparison of pain relief by rectal Diclofenac and intra muscular pethidine and comparison of their side effects. In a randomized single blind study 122 patients undergoing both emergency and elective CS for the first time were studied. The study group received 100 mg rectal diclofenac immediately after CS followed by 100 mg Diclofenac every 8 h for the first 24 h. The control group received 25 mg pethidine immediately after CS then 25 mg every 8 h for the first 24 h. Then the pain in 2 groups was evaluated by visual analogue score. The result showed that the visual analogue score for pain was significantly lower in diclofenac group. Incidences of vomiting and ileuses do not have any difference in two groups and was not reported early post-partum hemorrhage in any group. Rectal Diclofenac provides effective analgesia for CS pain and there was not significant difference between the 2 groups regarding incidence of vomiting and ileus.]]>Amboross, M.S. and P. Frederick,200118415441548Denovan, M., P. Dillon and L. Mcgurie,1987306070Hardman, J.G., L.E. Limbird and A.G. Gilman,200110th Edn.,pp: 701-709pp: 701-709Lim, N.L., W.K. Lo, J.L. Chong and A.X. Pan,200148383386Nisson, E., G. Lilja, A.S. Matthiesen, A.B. Ransjo Arridsson, K. Urnas-Moberg and A.M. Widstrom,199584140145Olofsson, C.I., M.H. Legeby, E.B. Nygards and K.M. Ostman,200088143146Power, I., W.A. Chambers, I.A. Greer, D. Ramage and E. Simon,199045916919Rashid, M. and H.M. Jaruidi,200021145149Rosariarius, M., G. Miralles, G.A. Baer and E. Palomaki,1985172306309Roseag, O.P., A.C.P. Lui, N.J. Ciccuti, P.R. Bagg, M.L. Crossan and B. Krepski,199744803809Sia, A.T., E. Thomas, J.L. Chong and C.C. Loo,1997386870Wittle, B. and R. Scott,199073864869