International Journal of Dairy Science1811-97431811-9751Asian Network for Scientific Information10.3923/ijds.2021.11.17Hassan ShehataSamera Nour SolimanTarek 12021161Background and Objective: Curcumin is a natural polyphenolic and using as a flavour of foods, that has a lot of therapeutic effects. The present work aimed that prepared caseinate-curcumin nanoparticles (CSCCMNPs) designed by desolvation technique and evaluated. Manufacture yoghurt incorporated by CSCCMNPs and study the effect of incorporation of it on properties of yoghurt. Materials and Methods: Prepared caseinate curcumin nanoparticles (CSCCMNPs) using a novel method by freeze-drying, for warmed ethanol 40% solution with co-dissolved sodium caseinate (NaCas) and curcumin (CCM). Investigate the effect of Incorporated CSCCMNPs in functional yoghurt on physicochemical, microbiological properties and acceptability evaluation. Results: The encapsulation efficiency ranged between 84.95 and 95.10%. The curcumin encapsulated in casein nanoparticles had higher biological activity, as assessed by antioxidant assays than free curcumin, likely due to the improved dispersibility. CSCCMNPs were bigger than those of NaCas processed at encapsulation conditions but were smaller than those of the native NaCas. Fortification of yoghurt with CSCCMNPs had a significant effect on the organoleptic properties of resultant yoghurt. Besides, body and texture were improved and the enhancement of yoghurt acceptability. Conclusion: Functional yoghurt of acceptable quality and high antioxidant activity could be prepared by CSCCMNPs.]]>Prasad, S. and B. Aggarwal,20112011Agarwal, R., K.G. Sudhir and R.B. Jai,201030457468Elsayed, A.S.I.,201672640Shehzad, A., G.Rehman and Y.S. Lee, 2013396977Gao, S., X. Duan, X. Wang, D. Dong and D. Liu et al.,201359739747Zhang, Y., C. Yang, W. Wang, J. Liu and Q. Liu et al.,20166112Flora, G., D. Gupta and A. Tiwari, 201330331368Bourassa, P., C.D. Kanakis, P.A. Tarantilis, M.G. Pollissiou and H.A. Tajmir-Riahi,201011433483354Mandeville, J.S., E. Froehlich and H.A. Tajmir-Riahi,200949468474Mohammadi, F., A.K. Bordbar, A. Divsalar, K. Mohammadi and A.A. Saboury, 200928117123Liu, A., H. Lou, L. Zhao and P. Fan,200640720727Shelma, R. and C.P. Sharma, 20102121332140Baglole, K.N., P.G. Boland and B.D. Wagner, 2005173230237Shah, C.P., B. Mishra, M. Kumar, K.I. Priyadarsini and P.N. Bajaj, 20089514261432Sari, T.P., B. Mann, R. Kumar, R.R.B. Singh, R. Sharma, M. Bhardwaj and S. Athira,201543540546Kotta, S., A.W. Khan, K. Pramod, S.H. Ansari, R.K. Sharma and J. Ali,20129585598Kralova, I. and J. Sjöblom, 20093013631383Dalev, P.G. and L.S. Simeonova, 199568203206Dende, C., J. Meena, P. Nagarajan, V.A. Nagaraj, A.K. Panda and G. Padmanaban,20177112Khadrawy, Y.A., M.M. El-Gizawy, S.M. Sorour, H.G. Sawie and E.N. Hosny, 201942194202McKinley, M.C.,200558112Santillán-Urquiza, E., H. Ruiz-Espinosa, A. Angulo-Molina, J.F.V. Ruiz and M.A. Méndez-Rojas, 20172017pp: 293-328pp: 293-328Sanguansri, P. and M.A. Augustin,200617547556Pan, K., Q. Zhong and S.J. Baek,20136160366043Yu, H. and Q. Huang,2010in vitro anti-cancer activity of curcumin encapsulated in hydrophobically modified starch.]]>119669674Soliman, T.N. and M.A.E.F. Hassan,201821448453Rai, S., A. Wahile, K. Mukherjee, B.P. Saha and P.K. Mukherjee,2006Nelumbo nucifera (sacred lotus) seeds.]]>104322327Lee, W.J. and J.A. Lucey,20102311271136Feldsine, P., C. Abeyta and W.H. Andrews,20028511871200Walia, A., H.N. Mishra and P. Kumar,20137120127Hamed, S.F., T.N. Soliman, L.K. Hassan and G. Abo-Elwafa, 201962301314SAS.,19995th Edn.,De Kruif, C.G. and T. Huppertz,20126046494655O'Connell, J.E., A.L. Kelly, M.A. Auty, P.F. Fox and K.G. de Kruif,20014944204423Esmaili, M., S.M. Ghaffari, Z. Moosavi-Movahedi, M.S. Atri and A. Sharifizadeh et al.,20114421662172Gomez-Estaca, J., M.P. Balaguer, R. Gavara and P. Hernandez-Munoz,2012288291Khopde, S.M., K.I. Priyadarsini, P. Venkatesan and M.N.A. Rao, 1999808591Kitts, D.D.,199916549554Takahashi, M., S. Uechi, K. Takara, Y. Asikin and K. Wada,20095791419146Ghorbanzade, T., S.M., Jafari, S. Akhavan and R. Hadavi,2017216146152Bonczar, G., M. Wszolek and A. Siuta,2002798591Foda, M.I., M. Abd El-Aziz and A.A. Awad,20072252259