International Journal of Cancer Research1811-97271811-9735Academic Journals Inc.10.3923/ijcr.2006.277.289JohnsonDavid B. 3200623Participants in the PLCO-Hawaii Cancer Screening Trial were given a self-administered 36-item health status questionnaire. This questionnaire includes eight health concepts relevant to the quality of life and self-perceptions of health. These are converted into two summary scales, self-perceived physical health status and self-perceived mental health status. The initial hypothesis of a negative effect of receiving an abnormal cancer-screening outcome to ones Health Related Quality of Life is not supported for either self-perceived physical health status or for self-perceived mental health status. Receiving notification of a cancer diagnosis does not produce an additional negative effect. There is no difference in health related quality of life between those in the screened group and controls who were not screened at any of the three time periods, baseline, first follow-up or second follow-up. There was no difference in health related quality of life between genders, age groups or ethnicities, except that in the screened group there was a reduction in the physical summary score for the oldest age group between base line and first follow-up assessments.]]>Katz, J.N., M.G. Larson and C.B. Phillips, 199230917925Perez-Stable, E.J., F. Sabogal and Otero-Sabogal, 199226832193223Vernon, S.W., B.C. Tilley, A.V. Neale and L. Steinfeldt,19855515631571Manocchia, M., M.S. Bayliss, J. Connor, S.D. Keller, J.C. Shiely and C. Tsai,19982nd Edn.,Stafford, A.M.,19781978pp: 12-22pp: 12-22Ware, J.E., K.K. Snow, M. Kosinski and B. Gandek,1993Ware, J.E., M. Kosinski and S.S.D. Keller,1994