International Journal of Biological Chemistry1819-155x2152-2561Science International10.3923/ijbc.2011.61.67Solanum torvum) Fruit Coat]]>SivapriyaM. DineshaR. HarshaR. GowdaS.S.T. SrinivasL. 1201151The main aim of this study was to find a new natural, non toxic, effective antibiotic from plant extract. In the present study, Solanum torvum (Sundakai) was selected. The antibacterial activity of different extracts of Solanum torvum (Sundakai) fruit coat was studied in vitro against human pathogenic strains. The Water Extract (WE) and Ethanol Water Extract (EWE) was found to be effective against all bacterial strains and inhibition is comparable to that of commercial antibiotics, choramphenicol and streptomycin. Initial screening of antibacterial activity was done by disc diffusion method in Nutrient agar medium. Minimum inhibition concentration was done serial dilution method. The MIC values of the Water Extract (WE), Ethanol Water Extract (EWE) and Ethanol Extract (EE) ranged from 9.6 to 19.2 μg mL-1. It was observed that there was a correlation between the amounts of polyphenols and flavonoids content and effective antibacterial activities of the inhibited extracts. These results indicate that Sundakai coat may be yet an another source of natural antibiotic. Further, this study reaffirms the ethanomedicinal property of S. torvum plant.]]>Ahmad, I., Z. Mehmood and F. Mohammad,199862183193Ambasta, S.P.,1992Sunilson, J.A.J., R. Suraj, G. Rejitha, K. Anandarajagopal, A.V.A.G. Kumari and P. Promwichit,2009In vitro antimicrobial evaluation of Zingiber officinale, Curcuma longa and Alpinia galanga extracts as natural food preservatives.]]>4192200Arthan, D., J. Svasti, P. Kittakoop, D. Pittayakhachonwut, M. Tanticharoen and Y. Thebtaranonth,2002Solanum torvum.]]>59459463Bonjar, G.H.S., 200435560Bradford, M.M.,197672248254Chung, K.T., T.Y. Wong, C.I. Wei, Y.W. Huang and Y. Lin,199838421464Davies, J.,1994264375382Daziel, J.M.,1937Dopke, W., C. Nogueiras and U. Hess,1975Solanum torvum.]]>30755755DuBois, M., K.A. Gilles, J.K. Hamilton, P.A. Rebers and F. Smith,195628350356Forbes, B.A., D.F. Sahm, A.S. Weissfeld and E.A. Trevino,19901990pp: 171-194pp: 171-194Iida, Y., Y. Yanai, M. Ono, T. Ikeda and T. Nohara,2005Solanum torvum.]]>5311221125Karou, D., H.M. Dicko, J. Simpore and S.A. Traore,20054823828Kivack, B. and T. Mert,2001Arbutus unedo by TLC-densitometry and colorimetry.]]>72656661Hara-Kudo, Y., A. Kobayashi, Y. Sugita-Konishi and K. Kondo,20046728202824Kujala, T.S., J.M. Loponen, K.D. Klika and K. Pihlaja,2000Beta vulgaris) root: Distribution and effect of cold storage on the content of total phenolics and three individual compounds.]]>4853385342Lu, Y., J. Luo, X. Huang and L. Kong,2009Solanum torvum and their cytotoxic activities.]]>7495101Nguelefack, T.B., C.B. Feumebo, G. Ateufack, P. Watcho and S. Tatsimo et al.,2008Solanum torvum Swartz (Solanaceae) in rats.]]>119135140Otshudi, A.L., A. Vercruysse and A. Foriers,200071411423Sadasivam, S. and A. Manickam,19962nd Edn.,Service, R.F.,1995270724727Shan, B., Y.Z. Cai, J.D. Brooks and H. Corke,2007in vitro antibacterial activity of dietary spice and medicinal herb extracts.]]>117112119Ilic, S.B., S.S. Konstantinovic and Z.B. Todorovic, 2004Linum capitatum kit. ]]>37377Valsaraj, R., P. Pushpangadan, U.W. Smitt, A. Adsersen and U. Nyman,1997587583Watt, J.M. and M.G. Breyer-Brandwijk,19622nd Edn.,Pages: 1457Pages: 1457WHO.,199671335336Wiart, C., S. Mogana, S. Khalifah, M. Mahan and S. Ismail et al.,2004756873Cordova, W.H.P., L.G. Mesa, A.L.P. Hill, C.N. Lima, G.D. Lamas, M.O. Suarez and R.S. Dominguez,2006Pluchea carolinensis (jacq.) g. don. ]]>3757761Woisky, R.G. and A. Salatino,19983799105Wu, C., F. Chen, X. Wang, H.J. Kim, G.Q. He, V. Haley-Zitlin and G. Huang,2006Tanacetum parthenium) extract and their chromatographic quantification.]]>96220227