Current Research in Neuroscience1996-3408xxxx-xxxxAcademic Journals Inc.10.3923/crn.2014.1.5El-DabahFouad H. ElgebaliMohammed E. 1201441Disorders of sodium and fluid regulation are common in patients with central
nervous system disorders. To avoid deleterious effects of hypo-osmolality, sodium
concentration must be preserved within normal range. It is hypothesized that,
hyponatremia measured at admission can be used as an indicator or predictor
for fatal outcome associated with head injuries. Thus, the present study designed
to test this hypothesis. Thirty patients with acute head injury were included
as a study group. In addition, another 30 apparently healthy subjects matched
for age and gender were included as a control group. Both serum and urine concentration
of sodium were done. Males were predominant; there was significant decrease
of blood sodium concentration and increase of urine sodium concentration in
study in comparison to control group. In addition, both blood and urine sodium
concentrations correlated with GCS. Furthermore, urine sodium had more significant
predicting power for mortality in those patients. Its predicating power was
better than GCS. Both urine sodium concentration and GCS are good predictors
of mortality in cases with acute head injury. Urine sodium concentration had
a better predictability than GCS.]]>Agha, A., M. Sherlock and C.J. Thompson,200598463464Agha, A., E. Thornton, P. O'Kelly, W. Tormey, J. Phillips and C.J. Thompson,20048959875992Bhardwaj, A. and J.A. Ulatowski,200410126131Bhardwaj, A.,200659229236Brimioulle, S., C. Orellana-Jimenez, A. Aminian and J.L. Vincent,200834125131Diringer, M.N. and A.R. Zazulia,200612117126Gilbert, P.T., R.C. Hawes and A.O. Beckman,195022772780Hoorn, E.J., J. Lindemans and R. Zietse,2006217076Palmer, B.F.,200314182187Rabinstein, A.A. and E.F. Wijdicks,20039290300Roca-Ribas, F., J.E. Ninno, A. Gasperin, M. Lucas and C. Llubia,200223992995Sherlock, M., E. O'Sullivan, A. Agha, L.A. Behan and D. Rawluk et al.,200664250254Tisdall, M., M. Crocker, J. Watkiss and M. Smith,2006185763Upadhyay, A., B.L. Jaber and N.E. Madias,2006119S30S35Wright, W.L.,201212466473Zada, G., C.Y. Liu, D. Fishback, P.A. Singer and M.H. Weiss,20071066671Zhang, W., S. Li, M. Visocchi, J. Jiang and X. Wang,200836648655