Current Research in Bacteriology1994-54262077-2122Asian Network for Scientific Information10.3923/crb.2008.23.27Porphyromonas asaccharolytica in Adult Periodontitis of Malaysian Samples]]>Himratul-AznitaW.H. MahmoodA.A. 1200811Bacterial toxin of Porphyromonas asaccharolytica
strains obtained from adult periodontitis were analysed using mouse
model. Results from subcutaneous injection with whole bacterial cells
of 108 and 1010 cells mL-1 failed to
induce any infection. However when bacterial concentration of 1012
cells mL-1 was used, all P. asaccharolytica strains
were able to induced the development of localized lesion on balb/c mice.
In addition, infected mice appeared cachectic with ruffled hair. Thus,
infection with the latter concentration was pathogenic and was dose dependent.
The toxin was also found to be heat labile for all strains. Therefore,
we conclude that the extracellularly toxin produced by P. asaccharolytica
of our local isolates which were obtained from adult periodontitis, is
virulent and heat labile.]]>Dahlèn, G. and A. Leonhardt,200621611Fletcher, H.M., H.A. Schenkein and F.L. Macrina,1994prtH) from Porphyromonas gingivalis.]]>6242794286Fletcher, H.M., H.A. Schenkein, R.M. Morgan, K.A. Bailey, C.R. Berry and F.L. Macrina,1995Porphyromonas gingivalis W83 Mutant Defective in the prtH gene.]]>6315211528Himratul-Aznita, W.H., T.B. Taiyeb Ali, K. Sushil, S.L.A. Zainuddin, A.A. Mahmood and A. Ansary,2005Prevotella intermedia clinical isolates in Malaysia.]]>5828831Himratul-Aznita, W.H. and A. Ansary,2006Prevotella intermedia isolates in Malaysia.]]>19799Jousimies-Somer, H.R., P.H. Summanen and H. Wexler,2003Bacteroides, Porphyromonas, Prevotella, Fusobacterium and other Anaerobic Gram Negative Bacteria.]]>2003pp: 880-901pp: 880-901Morizano, S., M. Enjoji, N. Sonoda, M. Fukushima, M. Kuniyoshi, K. Kotoh, M. Nakamuta and H. Nawata,2005Porphyromonas asaccharolytica as a putative pathogen.]]>44350353Neiders, M.E., P.B. Chen, H. Suido, H.S. Reynolds, J.J. Zambon, M. Shlossman and R.J. Genco,1989Bacteroides gingivalis.]]>24192198Van Steenbergen, T.J.M., P. Kastelein, J.J.A. Touw and J. de Graff,1982Bacteroides strains from periodontal pockets and other sites in experimentally induced skin lesions in mice.]]>174149