Asian Journal of Scientific Research1992-14542077-2076Asian Network for Scientific Information10.3923/ajsr.2022.22.30C. AzubuikeNkiruka B. MamaUchenna 12022151Background and Objective: Smokeless tobacco (snuff) use has been associated with many oral disease processes but there is a paucity of scientific information on its effects on dealers who process and package the substance for sales. The present study, therefore, investigated cytomorphometric changes in the exfoliated epithelial cells from the oral mucosa of snuff dealers. Materials and Methods: Study groups comprised 40 individuals (20 snuff dealers and 20 controls). Oral cytology smears were obtained using a wooden spatula and smeared on a microscope slide. Smears were fixed in 95% alcohol and stained with Giemsa stain for microscopical examination. Twenty cells were assessed for each of the participants and the cytoplasmic diameter (CD) and nuclear diameter (ND) were measured using AmScope Software. The ratios of nuclear diameter to cytoplasmic diameter (N/CR) were thereafter determined. The effect of age, sex, length of working experience (years of occupational exposure), snuff use, cigarette smoking and alcohol drinking habit on the parameters were also determined. Results: No significant difference was observed in CD, ND and N/CR of snuff dealers when compared to control (p>0.05). However, variations were only observed based on length of working experience and alcohol drinking habit (p<0.05). Conclusion: Data obtained from the present study has revealed variations in cytomorphometric parameters of exfoliated buccal cells of snuff dealers which is associated with years of occupational exposure and alcohol drinking habits.]]>de Geus, J.L., L.M. Wambier, A.D. Loguercio and A. Reis,201924e145e155Sabashvili, M., E. Gigineishvili, M. Jikia and T. Chitaladze,20182018Konstantinou, E., F. Fotopoulou, A. Drosos, N. Dimakopoulou and Z. Zagoriti et al.,2018118198203Ezzati, M. and A.D. Lopez, 2003127985Mathers, C.D. and D. Loncar,20062006Proia, N.K., G.M. Paszkiewicz, M.A.S. Nasca, G.E. Franke and J.L. Pauly,20061510611077Hatsukami, D.K., J.O. Ebbert, R.M. Feuer, I. Stepanov and S.S. Hecht,200733S368S378Fisher, M.A., J.E. Bouquot and B.J. Shelton,2005334552Phukan, R.K., M.S. Ali, C.K. Chetia and J. Mahanta,200185661667Henley, S.J., M.J. Thun, C. Connell and E.E. Calle,200516347358Gaddikeri, K., M. Abidullah and D. Bhorgonde,202012S86S90Bhavasar, R.S.K., S.K. Goje, V.K. Hazarey and S.M. Ganvir,201153158169Mathew, A.,202110114122Einstein, T.B.A. and B. Sivapathasundharam,2005164246Khot, K., S. Deshmane, K. Bagri-Manjarekar, D. Warke and K. Kotak,20156S22S24Buch, A.C., S.S. Patel, S.S. Chandanwale, H. Kumar, K.M. Patel and S.A. Bamanikar,20144138143Chaffee, B.W., E.T. Couch, M.V. Vora and R.S. Holliday,202187241253Noufal, A., A. George, M. Jose, M.A. Khader and C.S. Jayapalan,2014358995Kulkarni, P.G., P. Palakurthy, R.K. Nandan, T.M. Rao, D.S.P. Reddy and K. Muddana,201718722727Mendes, S.F., G. de Oliveira Ramos, E.R.C. Rivero, F. Modolo, L.J. Grando and M.I. Meurer,20112011Al-Abbadi, M.A.,201111828Suvarna, M., C. Anuradha, K.K. Kumar, P.C. Sekhar, K.L.P. Chandra and B.V.R. Reddy,201213337Singh, M., K. Sircar, A. Tandon, A. Chowdhry and D.B. Popli,201411649655Hecht, S.S., S.G. Carmella, S.E. Murphy, W.T. Riley and C. Le et al.,20071615671572Barzegari, A. and S. Mirdar,20189158163Asthana, S., S. Labani, U. Kailash, D.N. Sinha and R. Mehrotra,20192111621171Siddiqi, K., S. Husain, A. Vidyasagaran, A. Readshaw, M.P. Mishu and A. Sheikh,20202020Lee, P.N. and J. Hamling,20092009Maso, L.D., N. Torelli, E. Biancotto, M.D. Maso and A. Gini et al.,201631385393Nayar, A.K. and B.S. Sundharam,2003148793Ilayaraja, V., T.K. Priyadharshini, N. Ganapathy, A. Yamunadevi, J. Dineshshankar and T. Maheswaran,201852528Radhika, T., S. Hussain, S. Adithyan, N. Jeddy and S. Lakshmi,2019118488Shetty, D.C., V. Wadhwan, K. Khanna, A. Jain and A. Gupta,201576366Chaudhary, R., P. Sahni, M.D. Shylaja and A. Patel,201834043Nallamala, S., V. Guttikonda, P. Manchikatla and S. Taneeru,20179144148de Almeida Reis, S.R., A.R. do EspĂrito Santo, M.G.S. Andrade and M. Sadigursky,20062097102Srinivasamurthy, B.C., K. Balamurugesan, N. Sathishkumar, M. Prakash and R.V. Bhat,20202020Hoes, L., R. Dok, K.J. Verstrepen and S. Nuyts,20212021Brooks, P.J. and J.A. Theruvathu,200535187193Yu, H.S., T. Oyama, T. Isse, K. Kitagawa, T.T.P. Pham, M. Tanaka and T. Kawamoto,2010188367375Ogden, G.R.,200535169173Mello, F.W., G. Melo, J.J. Pasetto, C.A.B. Silva, S. Warnakulasuriya and E.R.C. Rivero,20192328492859