Asian Journal of Scientific Research1992-14542077-2076Asian Network for Scientific Information10.3923/ajsr.2021.1.5OnuohaE.C. IkeE.M. EledoB.O. HallieF.E. DiepreyeT.A. AdakaO.A. OsujiL.A. EdehF.K. Nelson-EbimieN. 12021141Background and Objective: Acute renal failure is a disorder with a feature of high urea and creatinine level with the outcome of an unexpected decrease in kidney function resulting in a significant decline in glomerular filtration rate. Apart from the major clinical importance of ABO blood group on blood transfusion and organ transplantation, there seem to be strong associations between blood group types and some diseases as a result of the carbohydrates compound found on the surface of the red blood cell membrane. This study aims to determine the effect of ABO blood group on acute renal disease patients. Materials and Methods: This case study was conducted on 56 patients with acute renal failure attending DEE Medical Center, Bukuru, Jos and Plateau State Nigeria from January-September, 2019. Ethical approval and patient consent statements were taken from everyone and the study was performed in the Medical Laboratory department of the hospital. Total 3 mL of patient blood was put into plain bottles. Serum was used to the determine level of urea and creatinine and ABO blood group was done with red cell samples by tube agglutination method. The data obtained were analyzed by SPSS software version 22. Results: Generally, the study revealed a strong association of ABO blood group on acute renal failure (p<0.001). However, Group B antigen was statistically discovered to cause the severity of acute renal failure (p<0.05). Conclusion: The results showed that blood group B individuals are more susceptible and suffer severely in renal disease than other blood group individuals as a result of the presence of D-galactose on its cell membrane.]]>Seeley, R.R., T.D. Stephens and P. Tate,20088th Edn.,Medugu, J.T., U. Abjah, I.A. Nasir, S. Adegoke and E.E. Asuquo,2016183842Zaman, R., M. Parvez, M.D. Jakaria and M.A. Sayeed,20157305310Eledo, B.O., D.O. Allagoa, I. Njoku, K.E. Dunga and C.I. Sylvester,20184398402Franchini, M. and M.L. Giancarlo,201351154515553Reilly, J.P., J.A. Brian, S.M. Nilam, D. Tam, D.N. Nguyen et al.,20151019111920Clausen, H. and S.I. Hakomori,198956120O'Donnell, J. and M.A. Laffan,200111343351Prasad, N., S. Barai, S. Gambhir, D. Parasar and M. Ora,201222103107Hilton, R.,2006333786790Cooper, C.M. and A.Z. Fenves,201510403408Ishani, A., J.L. Xue, J. Himmelfarb, P.W. Eggers, P.L. Kimmel, B.A. Molitoris and A.J. Collins,200920223228Thadhani, R., M. Pascual and J.V. Bonventre,199633414481460Tasaki, M., Y. Yoshida, M. Miyamoto, M. Nameta and L.M. Cuellar et al.,20098711251133Yang, M., X. Jingyuan, O. Yan, Z. Xiaoyan and S. Manman et al.,2017267360373612Fagherazzi, G., G. Gusto, F. Clavel-Chapelon, B. Balkau and F. Bonnet,201558519522Liumbruno, G.M. and M. Franchini,201311491499Alkout, A.M., C.C. Blackwell and D.M. Weir, 2000Helicobacter pylori.]]>18113641369Akhtar, K., G. Mehdi, R. Sherwani and L. Sofi,20102010Zhang, Z.F., S.H. Fan, Y.L. Zheng, J. Lu, D.M. Wu, Q. Shan and B. Hu,200947496501Fan, S.H., Z.F. Zhang, Y.L. Zheng, J. Lu and D.M. Wu et al.,200999196Yu, Y., F. Bai, Y. Liu, Y. Yang and Q. Yuan et al.,2015403287299Feng, Y., Y. Yu, S. Wang, J. Ren and D. Camer et al.,20165410271034Liu, C., Hu. Jie, M. Zhi, K. Hongjun and L. Hui et al.,201712593602Zhang, Z.F., S.H. Fan, Y.L. Zheng, J. Lu, D.M. Wu, Q. Shan and B. Hu,20095777317736