Asian Journal of Scientific Research1992-14542077-2076Asian Network for Scientific Information10.3923/ajsr.2019.84.90® and Artimisia annua Extract on Treatment of African Catfish Infected with Trypanosomiasis]]>Mohamed OsmanHussien Abd El-Fattah Noor El-DeenAhmed Esmael El-MetenawyTarek Mohamed Saad ZakiMona Mohamed KenawyAmany Abu BraykaAlaa El-Din Zakarya MahmoudAbeer E. 12019121Background and Objectives: Trypanosomiasis affecting fish caused by genus Trypanosoma which is considered as one of the most important protozoal disease affecting freshwater fishes. The present study aimed to investigate some trials for treatment of trypanosomiasis in catfish Clarias gariepinus with histopathological examination of the naturally infested catfish, C. gariepinus. Materials and Methods: A total number of 100 alive catfish (Clarias gariepinus) with 120±10 g weight were collected from private fish farm at Kafer El-Kheish governorate. The fish subjected to parasitological examination for the trypanosome species. For treatment trials, a total number of 120 catfish were divided into 4 groups each 10 with three replicate were used for treatment trials with Intropar® I/M, bath with Artimisia annua leaves ethanol extract (100 and 150 mg L1 for 120 min). Results: The main clinical and postmortem lesions of infected Clarias gariepinus were paleness of the outer body surface, eroded fins, gulping the atmospheric air. Histopathological investigation revealed degenerative, necrotic and inflammatory changes in skin, gills and all internal organs. Experimental infection of C. gariepinus, Oreochromis niloticus, gold fish Carassius auratus and male white mice to with Trypanosoma mukasai were carried out. The prevalence of trypanosomiasis in catfish C. gariepinus was 63%. The result of the treatment revealed that 150 mg L1 for 120 min was the treatment of choice for trypanosomiasis in C. gariepinus. Conclusion: It was concluded that the treatment of choice for trypanosomiasis in C. gariepius was bath treatment with Artimisia annua leaves ethanol extract (150 mg L1 for 120 min).]]>Eissa, I.A.M., A.F.H. Badran, A.S. Diab and F. Laya,20003401410Osman, H.A.M., N.G. Fadel and A.T. Ali,2009Clarias gariepinus infected with trypanosomiasis with special reference to immunization.]]>22164181El-Tantawy, S.A.M. and H.A.E. El-Sherbiny,2010Clarias gariepinus inhabiting Nile Delta water of the River Nile, Dakahlia province, Egypt.]]>6676696Muhammad, S., U.M. Chafe, M.R. Bello, Y.A. Adamu and A.A. Mohammed et al.,2017Clarias gariepinus, tilapia zillii, synodontis nigrata, bagras bayad and mormyrus rume of North Western Nigeria.]]>22027Nazrul Islam, A.K.M. and P.T.K. Woo,1991Carassius auratus infected with Trypanosoma danilewskyi.]]>113743Smit, N.J., A.J. Davies and J.G. van As,2000Schilbe intermedius) in the Okavango delta, Botswana.]]>20116119Woo, P.T.K.,1995Vol. 1,Pages: 816Pages: 816Overath, P., J. Haag, M.G. Mameza and A. Lischke,1999119591601Eissa, I.A.M.,2002Herbert, W.J. and W.H.R. Lumsden,1976Trypanosoma brucei: A rapid “matching” method for estimating the host's parasitemia.]]>40427431Lucky, Z.,1977Pages: 140Pages: 140Lied, E., J. Gjerde and O.R. Braekkan,1975Salmo gairdneri).]]>32699701Kabata, Z.,19851st Edn.,Ekanem, A.P. and E.A. Brisibe,2010Artemisia annua L. against monogenean parasites of Heterobranchus longifilis.]]>10611351139Bancroft, J., A. Stevens and D. Turner,19964th Edn.,Pages: 740Pages: 740Snedecor, G.W.,19644th Edn.,Mariam, N.E.,20012001Essam, S.A. and N.R.H. El-Khatib,20045103112El-Khatib, N.R.H. and N.S. Elias,200349167179Adawy, R.S.M. and K.A. Deeb,2007536580Ahmed, M.S.,200145117131Kidchakan, S.M.,2005Clarias macrocepholus x clarias gariepinus) and other freshwater fishes.]]>2005Kidchakan, S.M.,2005Clarias macrocepholus x clarias gariepinus) and other freshwater fishes.]]>2005Lom, J.,19791979pp: 269-337pp: 269-337Woo, P.T.K.,1981Trypanosoma danilewskyi in goldfish, Carassius auratus.]]>83343346Jones-Brando, L., J. D'Angelo, G.H. Posner and R. Yolken,2006In vitro inhibition of Toxoplasma gondii by four new derivatives of artemisinin.]]>5042064208Mishina, Y.V., S. Krishna, R.K. Haynes and J.C. Meade,2007Trypanosoma cruzi and Trypanosoma brucei rhodesiensein vitro growth.]]>5118521854Utzinger, J., S. Xiao, J. Keiser, M. Chen, J. Zheng and M. Tanner,2001818411860Ma, Y., D. Lu, X. Lu, L. Liao and X. Hu,2004Leishmania donovani both in vitro and vivo.]]>11712711273Ridley, R.G. and N. Hudson,19988346349Li, W., W. Mo, D. Shen, L. Sun and J. Wang et al.,20052005Ferguson, W.H.,20062nd Edn.,Pages: 163Pages: 163Bunnajirakul, S., D. Steinhagen, U. Hetzel, W. Korting and W. Drommer,2000Trypanoplasma borreli (Protozoa: Kinetoplastida) in susceptible common carp Cyprinus carpio.]]>39221229Supamattaya, K., J. Ruangsri, R. Ruggamol, A. Songpradit, S. Bhuvanath and W. Promkhunthong,2005Clarias macrocephalus x Clarias gariepinus) and other freshwater fishes.]]>27321332