Asian Journal of Plant Sciences 1682-3974 1812-5697 Asian Network for Scientific Information 10.3923/ajps.2020.54.62 G. Pavithra Bindal Sumant Rana Meenakshi Srivastava Seweta 1 2020 19 1 Endophytes are considered as plant mutualists which are living asymptomatically within plant tissues have been found in virtually all plant species. Endophytes receive nutrition and protection from the host plant while the host plant may benefit from enhanced competitive abilities and increased resistance to herbivores, pathogens and various abiotic stresses. This review focuses on the biology of endophytic fungi, their discovery, isolation, identification and diversity and their biological activities in environmental and agricultural sustainability. It also considers and their medicinal applications especially in the production of anticancer, antimicrobial, antioxidant and antiviral compounds. Endophytic fungi are one of the most creative groups of secondary metabolite producers that play important biological roles for human life. They are potential sources of novel natural agents for exploitation in the pharmaceutical industry, agriculture and in environmental applications. So, in this review we summarize their potential role against some important plant pathogens.

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