Asian Journal of Plant Sciences1682-39741812-5697Asian Network for Scientific Information10.3923/ajps.2011.86.91 Cucumis melo Seeds]]>GillN.S. BajwaJ. DhimanK. SharmaP. SoodS. SharmaP.D. SinghB. BaliM. 12011101The objective of present study was to evaluate the therapeutic potential of Cucumis melo seeds traditionally consumed and it was studied for free radical scavenging potential by hydrogen peroxide (H2O2) and DPPH method. Anti-inflammatory activity was evaluated using carrageenan-induced paw edema in rats. Analgesic activity was evaluated by tail immersion and tail flick methods in mice. The percentage scavenging of DPPH radical and H2O2 radical was 74.9% at 300 μg mL-1 and 58.91% at 200 μg mL-1 respectively concentration of. The H2O2 scavenging effect of MECM was 58.91%. The percentage reduction of paw edema was 56.6% at the dose of 300 mg kg-1. The high dose caused significant reduction in pain. Thus it can be concluded from the above results that Cucumis melo seeds have potent anti-inflammatory, antioxidant and analgesic activity.]]>Banerjee, D., S. Chakrabarti, A.K. Hazra, S. Banerjee, J. Ray and B. Mukherjee,20087805810Borgeat, P., M. Hamberg and B. Samuelsson,197625178167820Chen, K., G.W. Plumb, R.N. Bennett and Y. Bao,200596201205Davies, O.L., J. Raventos and A.L. Walpole,19461255264Dire, G.F., M.F.M.C. Coura, M.C.L. Almeida, S.D.D. Vasconcelos and P.R.A. Siqueira et al.,2007Sechium edule) extract on the plasmid Puc. 9.1 Dna.]]>67276Fard, M.H., S.L. Bodhankar and M. Dikshit,2008Lagenaria siceraria (Molina) standley on doxorubicin induced cardiotoxicity in rats.]]>4466471Gill, N.S., M. Garg, R. Bansal, S. Sood, A. Muthuraman, M. Bali and P.D. Sharma,2009Cucumis sativum L. seed extract in rats.]]>1131138Gill, N.S., K. Dhiman, J. Bajwa, P. Sharma and S. Sood,2010Benincasa hispida seed extract.]]>6652657Gill, N.S., P. Sharma, J. Bajwa, K. Dhiman, S. Sood, P.D. Sharma and M. Bali,2010Cucumis melo var. utilissimus seeds for the therapeutic potential.]]>5248255Goodwin, J.S. and M. Brodwick,199511577589Harborne, J.B.,1973pp: 49-188pp: 49-188Jayaprakasam, B., N.P. Seeram and M.G. Nair,2003Cucurbita andreana.]]>101116Kumar, P.S., S. Sucheta, V.S. Deepa, P. Selvamani and S. Latha,2008718261828Kumar, S., D. Kumar, M. Jusha, K. Saroha, N. Singh and B. Vashishta,2008Citrullus colocynthis (L.) Schrad. methanolic fruit extract.]]>58215220Mariod, A. and B. Matthaus,2008Cucumis melo var. agrestis oil.]]>155667Marzouk, B., Z. Marzouk, E. Haloui, N. Fenina, A. Bouraoui and M. Aouni,2010Citrullus colocynthis from Southern Tunisia.]]>1281519Miro, M.,19959159168Miliauskas, G., P.R. Venskutonis and T.A. van Beek,200485231237Peters, R.R., M.R. Farias and R.M. Ribeiro-do-Valle,1997Wilbrandia ebracteata.]]>63525528Peters, R.R., T.F. Saleh, M. Lora, C. Patry, A.J. De Brum-Fernandes, M.R. Farias and R.M. Ribeiro-do-Valle,1999Wilbrandia ebracteata on carrageenan-induced pleurisy in mice.]]>2624292437Rimm, E.B., A. Ascherio, E. Giovannucci, D. Spiegelman, M.J. Stampfer and W.C. Willett,1996275447451Sathishsekar, D. and S. Subramanian,2005Momordica charantia (bitter gourd) seeds on Streptozotocin induced diabetic rats.]]>14153158Semiz, A. and A. Sen,2007Momordica charantia L. (bitter melon) fruit extract.]]>6273277Singh, R.P., K.N.C. Murthy and G.K. Jayaprakasha,2002Punica granatum) peel and seed extracts using in vitro models.]]>508186Stahelin, H.B., K.F. Gey, M. Eichholzer, E. Ludin, F. Bernasconi, J. Thurneysen and G. Brubacher,1991133766775Uchikoba, T., H. Yonezawa and M. Kaneda,1998Benincasa hispida var. Ryukyu.]]>4922152219Wettasinghe, M. and F. Shahidi,2000701726Winter, C.A., E.A. Risley and G.W. Nuss,1962111544547Xanthopoulou, M.N., T. Nomikos, E. Fragopoulou and S. Antonopoulou,200942641646Yesil-Celiktas, O., E. Bedir and F. Vardar-Sukan,2007In vitro antioxidant activities of Rosmarinus officinalis extracts treated with supercritical carbon dioxide.]]>10114571464Patwardhan, B. and M. Hooper,199210911Valko, M., C.J. Rhodes, J. Moncol, M. Izakovic and M. Mazur,2006160140