American Journal of Food Technology1557-45711557-458XAcademic Journals Inc.10.3923/ajft.2011.103.116NasseriA.T. Rasoul-AminiS. MorowvatM.H. GhasemiY. 2201162Single-cell proteins are the dried cells of microorganism, which are used as protein supplement in human foods or animal feeds. Microorganisms like algae, fungi, yeast and bacteria, utilize inexpensive feedstock and wastes as sources of carbon and energy for growth to produce biomass, protein concentrate or amino acids. Since protein accounts for the quantitatively important part of the microbial cells, these microorganisms, also called single cell protein as natural protein concentrate. With increase in population and worldwide protein shortage the use of microbial biomass as food and feed is more highlighted. Although single cell protein has high nutritive value due to higher protein, vitamin, essential amino acids and lipid content, there is a doubt to be replaced to the conventional protein sources due to their high nucleic acid content and slower in digestibility. They also may be considered as foreign material by body, which may subsequently results in allergic reactions.]]>Alvarez, R. and A. Enriquez,198829208210Asenjo, J.A. and P. Dunnill,1981Cytophaga sp. and their application to the rupture of yeast cells.]]>2310451056Baldwin, C.V. and C.W. Robinson,1994Candida utilis using enzimatic pretreatment and high pressure homogenization.]]>434656Becker, E.W.,200725207210Becker, E.W.,1994Benaiges, M.D., J. Lopez-Santin and C. Sola,198911444451Bhalla, T.C., N.N. Sharma and M. Sharma,2007Callihan, C.D. and J.E. Clemmer,19791979pp: 271-273pp: 271-273Chandrani-Wijeyaratne, S. and A.N. Tayathilake,2000Candida tropicalis) isolated from Caryota urens (Khitul) toddy for single cell protein production.]]>287986Cooney, C.L.,19861986pp: 271-276pp: 271-276Cordero, B. and D. Voltolina,199716205211Curran, D.A., B.J. Tepper and T.J. Montville,19905515641566Damodaran, S. and J.E. Kinsella,198325761770Engler, C.R.,19851985pp: 305-324pp: 305-324Ferrianti, M.P. and A. Fiechter,1983pp: 201pp: 201Forage, A.J. and R.C. Righelato,19791979pp: 289-292pp: 289-292Hedenskog, G. and H. Morgen,197315129142Huang, Y.T. and J.E. Kinsella,1986344670674Humphrey, A.E.,19751975pp: 1-23pp: 1-23Kim, J.K. and H.Y. Chung,20019171181Kim, J.K., K.T. Tak and J.H. Moon,1998Kluyveromyces fragilis for the production of a highly nutritious protein diet.]]>184149Kunhi, A.A.M. and M.R.R. Rao,199591328Lee, B.H.,1996Mahasneh, I.A.,1997Chlorella sp. (Chlorophyta).]]>90153161Maul, S.B., A.J. Sinskey and S.R. Tannenbaum,1970228181181Middelberg, A.P.J.,199513491551Moebus, O. and M. Teuber,19831983pp: 102-107pp: 102-107Moulin, G., B. Malige and P. Galzy,1983662128Miller, B.M. and W. Litsky,1976Omar, S. and S. Sabry,19914170172Oura, E.,19831983pp: 3-42pp: 3-42Parajo, J.C., V. Santos, H. Dominguez and M. Vazquez,19954OH-based pretreatment for improving the nutritional quality of single cell protein.]]>55133149Radmer, R.J.,199646263270Raja, R., S. Hemaiswarya, N. A. Kumar, S. Sridhar and R. Rengasamy,2008347788Rasoul-Amini, S., Y. Ghasemi, M.H. Morowvat and A. Mohagheghzadeh,2009116129136Renaud, S.M., D.L. Parry and L.V. Thinh,19946337345Richmond, A.,2004Riviere, J.,19771977pp: 105-149pp: 105-149Roth, F.X.,198012719Rumsey, G.L., S.G. Hughes and J.L. Kinsella,1990Saccharomyces cerevisiae nitrogen by lake trout.]]>21205209Scrimshaw, N.S. and J.C. Dillen,19771977pp: 171-173pp: 171-173Sinclair, C.G. and D. Cantero,19901990pp: 65-113pp: 65-113Solomons, G.L.,19851985pp: 483-505pp: 483-505Stanbury, P.F., A. Whitaker and S.J. Hall,20002nd Edn.,Steinkraus, K.H.,19861986pp: 35-45pp: 35-45Trinci, A.P.J.,199296113Zadrazil, F. and A.K. Puniya,1995548587