American Journal of Drug Discovery and Development 2150-427x 2150-4296 Academic Journals Inc. 10.3923/ajdd.2014.194.201 Salmonella and Shiegella Isolates Among Diarrheal Patients in Gedo Hospital, West Shoa Zone, Oromia State, Ethiopia]]> Gunasekaran Thirumurugan Haileselassie Yonas Asefa Befikadu 3 2014 4 3 To evaluate the antimicrobial resistance profiling of bacterial strains from clinical isolates in Gedo Hospital, West Shoa Region, Oromia State, Ethiopia to create awareness of periodic antibiotic susceptibility testing, antimicrobial resistance among the health care providers. A convenience sample of patients who visited the adult outpatient department of Gedo hospital for diarrheal complaint was incorporated into the study. Isolation, identification of bacterial strains and antibiotic susceptibility tests were performed by the disk diffusion method recommended by the Clinical and Laboratory Standards Institute using commercial antibiotic discs. Out of 200 samples, 40 diarrheagenic bacteria were isolated and identified as Shiegella (22 = N) and Salmonella strains (18 = N). Shiegella and Salmonella strains were susceptible to gentamicin and ciprofloxacin, respectively but a high rate of resistance were observed to amoxicillin, chloramphenicol and tetracycline for both Shiegella and Salmonella strains. Notably, both bacteria have developed complete resistance to amoxicillin. Gentamicin may be the drug choice for Shiegella stains caused diarrhea and ciprofloxacin for the diarrhea caused by Salmonella in the study area. Antibiotics selection and treatment of infections based on bacterial strains identification and in vitro susceptibility testing rather than current empirical treatment.

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