Asian Journal of Biological Sciences1996-3351xxxx-xxxxScience International10.3923/ajbs.2019.477.481Monodora myristica) and African Basil (Ocimum gratissimum)]]>OkonkoLawrence Enyioha IkpemeEkei Victor KaluSuccess Eni 32019123Background and Objectives:Monodora myristica and Ocimum gratissimum are herbs widely consumed for nutritional and medicinal purposes in developing countries including Nigeria. This study was therefore designed to assess the effects of M. myristica and O. gratissimum on sperm parameters, testicular and epididymal weight of albino rats. Materials and Methods: Forty-nine male Albino rats (170-200 g) were divided randomly into 7 groups (A-G) of 7 animals each. Rats in group A served as the control; groups B and C were given 300 and 500 mg kg1 b.wt., of M. myristica, respectively; groups D and E received 300 and 500 mg kg1 b.wt., of O. gratissimum, respectively; while groups F and G received 300 and 500 mg kg1 b.wt., of M. myristica+ O. gratissimum, respectively. After 8 weeks of treatment, the animals were sacrificed and sperm samples collected for analysis. Results: Sperm analysis revealed that extract of M. myristica increased epididymal sperm motility, viability and count significantly (p<0.05) and dose dependently; whereas extract of O. gratissimum and the combined plant extract reduced sperm motility, viability and count significantly. Extract of O. gratissimuma lone increased sperm head abnormalities significantly. Conclusion: Findings of this study therefore, suggest that M. myristica promotes male fertility, whereas O. gratissimum and the combination of both herbs could have anti-fertility effects.]]>Ezeonwu, V.U.,2011Phyllanthus niruri in male albino rats.]]>415Ozulua, R.I. and P. Alonge,2008Piliostigma thonningii (Schum) increase locomotor activity in Sprague-Dawley rats.]]>77376Ugonna, E.V.,2013Ocimum gratissimum and Gongronema latifolium on fertility parameters: A case for bi-herbal formulation.]]>115Ibe, A.E. and M.I. Nwufo,2005306677Singh, A. and P.K. Singh,2009121324329Ijeh, I.I., O.D. Omodamiro and I.J. Nwanna,2005Ocimum gratissimum and Xylopia aethiopica.]]>4953956Uwakwe, A.A. and R.N. Nwaoguikpe,2008In vitro antisickling effects of Xylopia aethiopica and Monodora myristica.]]>2119124Ikpeme, E.V., O. Udensi, U.B. Ekaluo, E.A. Uyoh, B.O. Asuquo, F.V. Udoh and P.B. Udoh,2007Carica papaja seeds on the reproductive efficiency of male albino rats.]]>13365368Ikpeme, E.V., L.E. Okonko and O.U. Udensi,2016106874Ekaluo, U.B., Y.B. Ibiang, E.V. Ikpeme, B.E. Ekanem and F.A. Erem,20135914Choudhary, N., R. Goyal and S.C. Joshi,200829259262Akinola, O.B., O.S. Oladosu and O.O. Dosumu,2007Psidium guajava Linn.]]>14273276Cajuday, L.A. and G.L. Pocsido,2009Moringa oleifera Lam. (Moringaceae) on the reproduction of male mice (Mus musculus).]]>411151121Ekaluo, U.B., F.A. Erem, I.S. Omeje, E.V. Ikpeme, Y.B. Ibiang and B.E. Ekanem,201332123Uboh, F.E., E.E. Edet, M.U. Eteng and E.U. Eyong,2010P. guajava leaves and ascorbic acid on serum sex hormones levels in male and female rats.]]>6275279Okamura, A., M. Kamijima, E. Shibata, K. Ohtani and K. Takagi et al.,2005213129137Ekaluo, U.B., E.V. Ikpeme and E.A. Udokpoh,2009719Ekaluo, U.B., A.E. Udokpoh, U.U. Udofia and R.O. Ajang,2005118184Ikpeme, E.V., O. Udensi, U.B. Ekaluo and T.O. Solomon,20122157168Obianime, A.W., J.S. Aprioku and C.T.O. Esomonu, 2010Ocimum gratissimum L. leaves in male mice.]]>4809816Raji, Y., U.S. Udoh, O.O. Mewoyeka, F.C. Ononye and A.F. Bolarinwa,2003Azadirachta indica extract in rats.]]>32159165Oze, G., H. Nwanjo, R. Oze, E. Akubugwo, E. Orisakwe and P. Aka,2007Alstonia boonei (De-wild) stems bark in male rats.]]>2007