Asian Journal of Biological Sciences1996-3351xxxx-xxxxScience International10.3923/ajbs.2011.84.89Bridelia retusa Bark in Albino Rats]]>TatiyaAnil U. DeoreUjwaldip V. JainPankaj G. SuranaSanjay J. 1201141In the present study, Bridelia retusa bark was screened for their hypoglycemic potential on normal, oral glucose tolerance study and alloxan induced rats. Albino rats were divided into groups (n = 6) received different treatments consisting of control, methanolic, pet-ether and n-butanol extracts (at a dose of 200 and 400 mg kg-1) and standard drug Glibenclamide (5 mg kg-1 p.o.). Estimation of blood glucose level was done by GOD/POD method. Results indicated that B. retusa extracts does not affect blood glucose level on normal rats but in Alloxan induced diabetic rats n-butanol extract showed significant (p<0.001) fall of blood sugar level. However, the effect of drug was less than standard. Phytochemical analysis has revealed the presence of steroids, triterpenoids, tannins and flavonoids as major constituents.]]>Abdel-Hassan, I.A., J.A. Abdel-Barry and S.T. Mohammeda,2000Citrullus colocynthis fruit aqueous extract in normal and alloxan diabetic rabbits.]]>71325330Adhav, M., C.M. Solanki, B. Patel and A. Gharia,2002Bridelia retusa (L) spreng, Veg.]]>18479486Anonymous,1958pp: 295-296pp: 295-296Bagad, Y.M.,2007Bridelia airyshawii. (Euphorbiaceae).]]>2007Goke, B., H. Fuder, G. Wieckhorst, U. Theiss and E. Striddle et al.,199556493501Jafri, M.A., M. Aslam, K. Javed and S. Singh,1999Pnica granatum Linn. (flower) On blood glucose level in normal and alloxan induced diabetic rats.]]>70309314Jain, A., S.S. Katewa, P.K. Galav and P. Sharma,2005102143157Khosia, P., D. Gupts and R.K. Nagpal,199539173174Kirtikar, K.R. and B.D. Basu, 19351st Edn.,Diatewa, M., C.B. Samba, T.C.H. Assah and A.A. Abena,2004Cogniauxia podoleana Baillon in normal and alloxan-induced diabetic rats.]]>92229232Mehare, I.D. and B.C. Hatapakki,2003Bridelia retusa.]]>46568Raghunathan, M. and N. Raghunathan,19921344Sokeng, S.D., B. Rokeya, M. Mostafa, N. Nahar, M. Mosihuzzaman, L. Ali and P. Kamatchouing,2005Bridelia ndellensis ethanol extract and fraction in streptozotocin-induced diabetic rats.]]>294102Stumvoll, M., A. Mitrakou, W. Pimenta, T. Jenssen and H. Yki-Jarvinen et al.,200023295301Suba, V., T. Murugesan, R.R. Bhaskara, L. Ghosh and M. Pal et al.,2004Barleria lupulina extract in rats.]]>714Szkudelski, T.,200150537546