Asian Journal of Biotechnology1996-0700xxxx-xxxxKnowledgia Review10.3923/ajbkr.2009.154.162Phyllanthus amarus]]>AnnamalaiA. LakshmiP.T.V. 4200914One of the most widely used herbs in Ayurvedic medicine
is Phyllanthus amarus, which is predominantly grown in Indian subcontinent.
Since, the market surveillance of herbal drugs is reported to contain
minimum 0.5% of phyllanthin, demands increased production of this herb,
which could be achieved by standard agrotechniques. Moreover, since, it
is also desirable to check for the effect of these improved measures on
the bioactive compound-phyllanthin, an effort was aimed at investigating
a standard strategy to quantify the principle compound. Hence, a detailed
investigation was adopted to provide a comparative quantification of phyllanthin
through High Performance Thin Layer Chromatography (HPTLC) and High Performance
Liquid Chromatography (HPLC) from different organs of P. amarus
grown with improved agrotechniques. However, it revealed to be more effective
through HPLC especially higher in the leaves as against the analysis through
HPTLC. ]]>Annamalai, A.,2002Phyllanthus amarus schum. and thonn.]]>2002Annamalai, A., P.T.V. Lakshmi, D. Lalithakumar and K. Murugesan,2004Phyllanthus amarus (Bhumyamalaki) in sandy loam soil.]]>26717720Benoit, L., M. Linda, B. Hooper, E.P. Mummaa, James and P. Geaghanb,200549415423Blumberg, B.S., I. Millman, P.S. Venkateswaran and S.P. Thyagarajan,1990Phyllanthus amarus.]]>88692Deb, S. and S.K. Mandal,1996Phyllanthus amarus (Bhumiamalaki) and in polyherbal formulations.]]>33415416Huang, R.L., Y.L. Huang, J.C. Ou, C.C. Chen, F.L. Hsu and C. Chang,2003Phyllanthus species for anti-human hepatitis B virus in vitro.]]>17449453Kassuya, C.A.L., F.P.L. Daniela, V.M. Lucilia, G.R. Vera-Lucia and B.C. Joao,2005Phyllanthus amarus.]]>71721726Kiritikar, K.R. and B.D. Basu,20012nd Edn.,Khatoon, S., V. Rai, A.K.S. Rawat and S. Mehrotra,2006Phyllanthus species.]]>1047986Krithika, R., R. Mohankumar, R.J.Verma, P.S. Shrivastav, I.L. Mohamad, P. Gunasekaran and S. Narasimhan,2009181351358Kumar, K.B.H. and R. Kuttan,2005Phyllanthus amarus against cyclophosphamide induced toxicity in mice.]]>12494500MacBae, W.D., J.B. Hudson and G.H. Towers,198822143172Mehrotra, R., S. Rawat, D.K. Kulshreshtha, P. Goyal, G.K. Patnaik and B.N. Dhawan,1991In vitro effect of Phyllanthus amarus on Hepatitis B virus.]]>937173Murali, B., A. Amit, M.S. Anand, T.K. Dinesh and D.S. Samiulla,2001Phyllanthus amarus.]]>15559Murugaiyah, V. and K.L. Chan,2006Phyllanthus niruri.]]>7212621267Negi, A.S., J.K. Kumar, S. Luqman, K. Shanker, M.M. Gupta and S.P.S. Khanuja,200828746772Rajasubramaniam, S. and P.P. Saradhi,1997Phyllanthus fraternus: A plant with anti-hepatitis viral activity.]]>63540Raphael, K.R., M.C. Sabu and R. Kuttan,2002Phyllanthus amarus schum and thonn on alloxan induced diabetes mellitus in rats and its relation with antioxidant potential.]]>40905909Row, L.R., C. Srinivasulu, M. Smith and G.S.R. Subba Rao,1966Phyllanthus niruri (Linn) The constitution of phyllanthin.]]>2228992908Sane, R.T., L.C. Jyoti and V.V. Kuber,1997Phyllanthus amarus-Part-II.]]>34654655Sharma, A., R.T. Singh and S.S. Handa,1993Phyllanthus amarus.]]>4226229Shead, A., K. Vickery, A. Pajkos, R. Medhurst, J. Freiman, R. Dixon and Y. Cossart,1992Phyllanthus amarus plant extracts on duck Hepatitis B virus in vitro and in vivo.]]>18127138Srivastava, V., M. Singh, R. Malasoni, K. Shanker and R.K. Verma et al.,2008Phyllanthus species by a simple chiral densitometric method.]]>314755Syamasundar, K.V., B. Singh, R.S. Thakur, A. Husain, Y. Kiso and H. Hikino,1985Phyllanthus niruri herbs.]]>144144Thyagarajan, S.P., T. Thirunalasundari, S. Subramanian, P.S. Venkateswaran and B.S. Blumberg,1988Phyllanthus amarus on chronic carriers of hepatitis B virus.]]>332764776Unander, D.W. and B.S. Blumberg,1991In vitro activity of Phyllanthus (Euphorbiaceae) species against DNA polymerase of Hepatitis viruses: Effect of growing environment and inter and intraspecific differences.]]>45225242Verpoorte, R. and P.P. Dihal,198721315318Bowen, G.D.,19801980pp: 283-304pp: 283-304