Asian Journal of Biochemistry1815-99231815-9931Academic Journals Inc.10.3923/ajb.2016.1.13Hypericum hookerianum and its Glycosidic Flavonoid Enriched Extract in Reserpine Induced Swiss Albino Mice]]>SubakanmaniS. MuruganS. DeviP. Uma 12016111The purpose of the study was to investigate the anti-depressant like effect of ethanolic extract of H. hookerianum (EEHh 200 and 400 mg kg1 p.o.,) and its glycosidic flavonoid enriched extract of ethanolic extract of H. hookerianum (GFHh 100 mg kg1 p.o.,) in reserpine induced (2 mg kg1 i.p.,) Swiss albino mice. The flavonoidal constiteuents in EEHh and GFHh was confirmed by HPLC. The behavioral analysis of forced swimming test, tail suspension test, locomotor activity in mice has been conducted. Brain superoxide dismutase, catalase, glutathione and lipid peroxidation were estimated biochemically. Brain monoamine oxidase (A and B) activity has been carried out by double beam spectrophotometer. All the values in this study indicated that the GFHh posses well specified antidepressant activity than EEHh due to higher concentration of flavonoids as confirmed by HPLC.]]>Bao, S., J. Fei, J. Shen, S.J. Gong, H. Fang and A.J. Husband,200684537542Bolandghamat, S., A. Moghimi and M. Iranshahi,2011Pinus eldarica Medw.) on reserpine-induced depression-like behavior in male wistar rats.]]>7248253Bourin, M., F. Chenu, N. Ripoll and D.J.P. David,2005164266269Chambers, C.D., S. Hernandez-Diaz, L.J. Van Marter, M.M. Werler, C. Louik, K.L. Jones and A.A. Mitchell,2006354579587Chimenti, F., F. Cottiglia, L. Bonsignore, L. Casu and M. Casu et al.,200669945949Cryan, J.F., A. Markou and I. Lucki,200223238245Cryan, J.F., M.E. Page and I. Lucki,2005182335344Darvesh, A.S., R.T. Carroll, A. Bishayee, W.J Geldenhuys and C.J. Van der Schyf,201010729745Dhingra, S. and M. Parle,201222286292Dimpfel, W.,200916287294Dunlop, B.W. and C.B. Nemeroff,200764327337Ellman, G.L.,1959827077Fava, M. and A.J. Rush,200675139153Haenen, G.R.M.M. and A. Bast,1999301490503Hasler, A., O. Sticher and B. Meier,1992Ginkgo biloba by high-performance liquid chromatography.]]>6054148Kakkar, P., B. Das and P.N. Viswanathan,198421130132Knoll, J.,199743482493, (In Russian)Krishnan, K.R.,19981998pp: 239-249pp: 239-249Lepine, J.P. and M. Briley,2011737Yu, L., X. Jiang, M. Liao, R. Ma and T. Yu,20112142148Lowry, O.H., N.J. Rosebrough, A.L. Farr and R.J. Randall,1951193265275Mancuso, C., T.E. Bates, D.A. Butterfield, S.C. Calafato and C. Cornelius et al.,20071619211931Mayo, J.C., R.M. Sainz, I. Antolin, F. Herrera, V. Martin and C. Rodriguez,20025917061713McGrath, P.J., J.W. Stewart, W. Harrison and F.M. Quitkin,198723169172Mukherjee, P.K. and B. Suresh,2000Hypericum hookerianum leaf and stem extracts.]]>66169Mukherjee, P.K., G.S. Saritha and B. Suresh,2001Hypericum hookerianum.]]>72558560Naidu, P.S., A. Singh and S.K. Kulkarni,2004705967Newman, D.J., G.M. Cragg and K.M. Snader,20036610221037Pan, Y., L. Kong, X. Xia, W. Zhang, W. Xia and F. Jiang,200582686694Pandey, K.B. and S.I. Rizvi,20092270278Petit-Demouliere, B., F. Chenu and M. Bourin,2005177245255Porsolt, R.D., A. Bertin and M. Jalfre,1977229327336Porsolt, R.D., G. Anton, N. Blavet and M. Jalfre,197847379391Porsolt, R.D., G. Brossard, C. Hautbois and S. Roux,20012001Porsolt, R.D., M. le Pichon and M. Jalfre,1977266730732Reddy, D.S. and S.K. Kulkarni,1998799215229Saaby, L., H.B. Rasmussen and A.K. Jager,2009Calluna vulgaris (L.) Hull.]]>121178181Dongre, S.H., S. Badami, S. Natesan and R.H. Chandrashekhar,2007Hypericum hookerianum stem against Ehrlich ascites carcinoma in swiss albino mice.]]>103354359Schurr, A. and A. Livne,19762512011203Sinha, A.K.,197247389394Steru, L., R. Chermat, B. Thierry and P. Simon,198585367370Stevenson, D.E. and R.D. Hurst,20076429002916Subakanmani, S. and P. Umadevi,2012Hypericum hookerianum in stress induced Swiss albino mice.]]>3219225Vijayan, P., C. Raghu, G. Ashok, S.A. Dhanaraj and B. Suresh,20041202429WHO.,20062006Wouters, J.,19985137162Xu, Q., L.T. Yi, Y. Pan, X. Wang and Y.C. Li et al.,2008Magnolia officinalis in stressed rodents.]]>32715725Yamada, M. and H. Yasuhara,200425215221Yan, B., D.Y. Wang, D.M. Xing, Y. Ding, R.F. Wang, F. Lei and L.J. Du,200478319325Yu, Z.F., L.D. Kong and Y. Chen,2002Curcuma longa in mice.]]>83161165Zhang, Z.J.,20047516591699