Asian Journal of Animal and Veterinary Advances1683-99191996-3289Academic Journals Inc.10.3923/ajava.2014.253.261FUT1 Gene M307 and its Relationship with Partial
Immune Indexes and Economic Traits in Yorkshire Pigs]]>ZhuShiping LiuYing DongWenhua ZhengXianrui ZhuGuoqiang WuShenglong BaoWenbin 4201494To assess the feasibility of FUT1 gene M307 as a disease resistance
genetic marker in Yorkshire pigs, this experiment adopted PCR-RFLP method to
investigate the genetic variations at M307 of FUT1 gene in purebred Yorkshire
(total 218 individuals), determined partial biochemical parameters and important
cytokines using the automatic blood cell analyzer and ProCarta immunoassay kits
and assayed a number of economic traits including eye muscle thickness, backfat
thickness, growth rate and reproductive performance. This study also analyzed
the relationship between polymorphism of FUT1 gene M307 and partial immune
indexes, vital economic traits. The results showed that there were three genotypes
(AA, AG and GG) in Yorkshire test groups, in which the allele G was dominant
one. FUT1 gene M307 deviated from Hardy-Weinberg equilibrium (p<0.01)
in the population. Correlation analysis showed that the level of thrombocytocrit
(PCT) in AG, GG genotype individuals were significantly higher than that in
AA genotype individuals (p<0.05), while there were no significant difference
between AG and GG genotypes (p>0.05). The individuals with GG genotype were
significantly higher than those with AG genotype (p<0.01) in IFN-γ,
TGF-β and TNF-α. In terms of the age at 100 kg, individuals with AA
type were significantly higher than those with AG type (p<0.05), the average
age at 100 kg of AA type individuals was 4.23 days less than GG type individuals.
From the 3rd-5th parity, the Total Number Born (TNB) and Number Born Alive (NBA)
demonstrated a trend of AA>AG>GG, individuals with AA type were significantly
higher than those individuals with GG type (p<0.05) in TNB and NBA at 3rd
and 5th parities. These results indicated that AA genotype, as an ETEC F18 resistance
genetype, would also improve growth rate and reproduction performance of Yorkshire
pigs, but reduce their general disease resistance ability.]]>Bao, W.B., S.L. Wu, H.H. Musa, G.Q. Zhu and G.H. Chen,2008FUT1) gene in Asian wild boar and Chinese and Western commercial pig breeds.]]>125427430Bao, W.B., S.L. Wu, J.J. Cao, X.G. Huang and G.H. Chen,2009FUT1 gene and its relationship with litter size in Duroc pigs.]]>4557Bao, W.B., L. Ye, J. Zhu, Z.Y. Pan, G.Q. Zhu, X.G. Huang and S.L. Wu,2012FUT1 gene as a genetic marker for disease resistance breeding of sutai pigs.]]>3942234228Bao, W.B., L. Ye, J. Zhu, Z.Y. Pan, G.Q. Zhu, X.G. Huang and S.L. Wu,2012FUT1 gene and its relationship with some immune indexes in Sutai pigs (Duroc x Meishan).]]>49665673Chevillard, C., S. Henri, F. Stefani, D. Parzy and A. Dessein,2002IFN-γ) promoter.]]>295356Jiang, X.P., Y.G. Liu, Y.Z. Xiong and C.Y. Deng,2005FUT1 gene on meat quality and carcass traits in swine.]]>27566570Li, M.O., Y.Y. Wan, S. Sanjabi, A.K.L. Robertson and R.A. Flavell,20062499146Meijerink, E., R. Fries, P. Vogeli, J. Masabanda and G. Wigger et al.,1997Escherichia coli F18 receptor (ECF18R) loci. ]]>8736741Ouyang, J.X., L.X. Wang and C.J. Lin,2004312325Pan, X.M., Y.X. Dou and X.P. Cai,200863639Sambrook, J. and D.W. Russell,20013rd Edn.,Pages: 2344Pages: 2344Shi, Q.S., S.Q. Huang, X.C. Liu, C.Q. He and J. Jiang,2003E. coli F18 receptor gene in different pig breeds.]]>30221224Tang, G.Q., J.Y. Wang and X.W. Li,2002292932Tracey, K.J., F. Lane and C.M. Hilkens,1990864817211728Vogeli, P., E. Meijerink, R. Fries, S. Neuenschwander, N. Vorlander, G. Stranzinger and H.U. Bertschinger,1997E. coli F18 receptors: A breakthrough in the struggle against edema disease and post-weaning diarrhea in swine.]]>139479484Wang, L.Y.,2000322021Xiang, Q. and M.J. Liu,2013194445Yan, X.M., J. Ren, Y.M. Guo, N.S. Ding and K.F. Chen et al.,2003FUT1) gene in 26 pig breeds. ]]>30830834Yeaman, M.R. and A.S. Bayer,2000Staphylococcus aureus, platelets and the heart.]]>2281298Zhu, H.Y., S. Zhao, W. Zhao and Y.H. Su,2009FUT1 gene and its relationship with litter size in Northeast Hebao pigs.]]>113