Asian Journal of Animal and Veterinary Advances1683-99191996-3289Academic Journals Inc.10.3923/ajava.2008.206.213 Pasteurella multocida ]]>ShayeghJ. AtashpazS. HejaziM.S. 4200834To learn more about the virulence of Pasteurella
multocida isolated from sheep, phenotype, capsular type and some virulence
factors (Pfha1, HgbB, TbPA and ToxA) of ovine
Pasteurella multocida is described in this study. Forty seven isolates
of Pasteurella multocida were isolated from clinically healthy
and diseased sheep. The isolates belonged to biovars 2(4.25%), 3(21.27%),
4(19.14%), 5(2.1%), 6(27.65%), 7(23.4%) and 11(2.1%). Capsular typing
of isolates by PCR demonstrated two capsular types A (39), D (3) including
5 untyped with 83.3%, 6.3% and 10.6% prevalence, respectively. Among 4
virulence genes detected by PCR, we found a remarkable high prevalence
of TbPA (69.4%) and ToxA (72.2%) genes in diseased animals.
The high prevalence of ToxA and TbPA among diseased sheep
may imply to important role of these genes in epidemiological and virulence
of P. multocida isolates in sheep. Additionally, The high prevalence
of P. multocida type A ToxA(+) in diseased sheep found in
this study is noticeable and attribute to important role of P. multocida
type A ToxA(+) in respiratory infection among sheep.]]>Baalsrud, K.J.,1987121350353Barrow, G.I. and R.K.A. Feltham,20062006Blackall, P.J., J.L. Pahoff, D. Marks, N. Fegan and C.J. Morrow,1995P. multocida isolates from fowl cholera outbreaks on seven turkey farms.]]>12135138Blackall, P.J., J.L. Pahoff and R. Bowles,1997P. multocida isolates from Australian pigs.]]>57355360Carter, G.R. and M.C.L. De-Alwis,19891989pp: 131-160pp: 131-160Chanter, N. and J.M. Rutter,1989P. multocida.]]>1989pp: 161-195pp: 161-195Cox, A.J., M.L. Hunt, J.D. Boyce and B. Adler,2003HgbBI a new hemoglobin binding protein of Pasteurella multocida.]]>34287296Ewers, C., A. Lubke-Becker, A. Bethe, S. Kiebling, M. Filter and L.H. Wieler,2006Pasteurella multocida strains isolated from different hosts with various disease status.]]>114304317Fegan, N., P.J. Blackall and J.L. Pahoff,1995Pasteurella multocida isolates from Australian poultry.]]>47281286Frank, G.H.,19891989pp: 197-222pp: 197-222Fussing, V., J.P. Nielsen, M. Bisgaard and A. Meyling,1999Pasteurella multocida sp. multocida in Denmark.]]>656174Harper, M., J.D. Boyce and B. Adler,2006Pasteurella multocida pathogenesis: 125 after pasteur.]]>265110Lichtensteiger, C.A., S.M. Steenbergen, R.M. Lee, D.D. Polson and E.R. Vimer,1996Pasteurella multocida.]]>3430353039Mutters, R., P. Ihm, S. Pohl, W. Frederiksen and W. Mannheim,1985Pasteurella Trevisan 1887 on the basis of deoxyribonucleic acid homology, with proposals for the new species Pasteurella dagmatis, Pasteurella canis, Pasteurella stomatis, Pasteurella anatis and Pasteurella langaa.]]>35309322Ogunnariwo, J.A. and A.B. Schryvers,2001Pasteurella multocida.]]>183890896Rudolph, K.M., D.L. Hunter, W.J. Forey, E.F. Cassirer and R.B. Rimler et al.,2003Pasteurella sp. between free-ranging bighorn sheep and feral goats.]]>39897903Townsend, K.M., J.D. Boyce, J.Y. Chung, A.J. Frost and B. Adler,2001Pasteurella multocida cap loci and development of a multiplex capsular PCR typing system.]]>39924929Veken, J.W., B. Oudega, J. Luirink and F.K. de Graaf,1994Pasteurella multocida serotype B: 2,5, a strain which causes haemorrhagic septicaemia in buffalo and cattle.]]>115253257Weiser, G.C., W.J. DeLong, J.L. Paz, B. Shafii and W.J. Price et al.,2003Pasteurella multocida associated with pneumonia in bighorn sheep.]]>39536544Zamir-Saad, M., W.M. Effendy, M.A. Maswaiti, N. Salim and A.R. Sheikh-Omer,1996Pasteurella multocida.]]>152453458