Asian Journal of Animal and Veterinary Advances1683-99191996-3289Academic Journals Inc.10.3923/ajava.2008.162.168Shokouhi Sabet JalaliFarnood SaifzadehSiamak TajikHossein HobbiSolmaz 3200833The aim of this investigation was a clinical and microbiological
evaluation of the accelerating effect of Iranian garlic (1% aqueous extract)
on the burn wound healing in dog. Ten apparently healthy mongrel dogs
of both sexes, with mean weight of 20 ± 2.25 kg were studied. Based
on Hoekstra standard model, two rectangular (2x3 cm2) wounds
were created on the left (experiment) and right (control) caudodorsal
areas of each dog. The experiment wounds were treated with 0.5 mL of 1%
aqueous garlic extracts every 3 other day for 21 days. In the control
group, the wounds were washed with normal saline at same frequency and
time of day. The wounds were photographed and compared for rate of wound
contraction with digital scanning software. The significant differences
were seen between the experiment and control wounds for the rate of contraction.
Moreover, a lesser total count of microorganisms was found (4 ± 0.5x104
cm-2) when garlic extract was applied on burn wounds compared
to the control wounds (2 ± 0.5x105 cm-2) on
the day 21 (p<0.05). According to the results of this study, topical
usage of aqueous garlic extract could enhance burn wound healing process
in the dog.]]>Akgul, A.,1993pp: 79-81pp: 79-81Ankri, S. and D. Mirelman,19991125129Baghalian, K., S.A. Ziaib, M.R. Naghavic, H. Naghdi-Badib and A. Khalighia,2005Allium sativum L.) ecotypes.]]>103155166Baruchin, A.M., A. Sagi, B. Yoffe and M. Ronen,200127781782Brans, T.A., R.P. Dutrieux, M.J. Hoekstra, R.W. Kreis and J.S. du Pont,199420S48S51Celiini, L., B. Di Campli, M. Masulli, S. Di Bartolomeo and N. Aliocati,1996Helicobacter pylori by Garlic extract.]]>13273277Chowdhury, A.K., M. Ahsan, S.N. Islam and Z.U. Ahed,1991933336Cooper, A.J.L. and J.T. Pinto,200569209220Dietz, D.M., J.R. Varcelotti and K.R. Stahlfeld,200430612613Ellmore, G.S. and R.S. Feldberg,1994Allium sativum).]]>818994Gonzalez-Fandos, E., M.L. Garcia-Lopez, M.L. Sierra and A. Otero,199477549552Graham, H.D. and E.J.F. Graham,1987Aspergillus parasiticus growth and toxin production by garlic.]]>8101108Haciseferogullari, H., M. Ozcan, F. Demir and S. Calisir,2005Allium sativum L.).]]>68463469Harris, L.C., S.L. Cottrel and S. Plummer, 2001Allium sativum (garlic).]]>57282286Holzgartner, H., U. Schmidt and U. Kuhn,19923A88Hosseini, A., 19881st Edn.,pp: 26-32pp: 26-32Heinach, P.K. and D.L. Larry,1996Allium sativum L. and Related Species.]]>2nd Edn.,pp: 62-64pp: 62-64Lawson, L.D.,19961996pp: 37-108pp: 37-108Naguib, Y.,2002526Reuter, H.D., H.P. Koch and L.D. Lawson,19961996pp: 135-213pp: 135-213Saifzadeh, S., A. Tehrani, F. Shokouhi Sabet Jalali and R. Oroujzadeh,2006511011104Sardari, K., A. Mirshahi, M. Maleki, M.R. Aslani and M.N. Barjasteh,2006Histological aspects).]]>1598102Sardari, K., M.M. Dehgan, M. Mohri, M.R. Emami and A. Mirshahi et al.,200615231235Shadkchan, Y., E. Shemesh, D. Mirelman, T. Miron, A. Rabinkov, M. Wilchek and N. Osherov,2004Aspergillus sp. in vitro and in a murine model of disseminated aspergillosis.]]>53832836Sharma, G.P. and S. Prasad,2001Allium sativum) cloves by microwave-hot air combination.]]>5099105Shukla, Y. and P. Taneja,2002313136Sivam, G.P., 2001Helicobacter pylori and other bacterial infections by garlic.]]>1311106S1108SZaika, L.L.,1988997118