Asian Journal of Agricultural Research1819-1894xxxx-xxxxKnowledgia Review10.3923/ajar.2016.114.125Coturnix coturnix japonica) Diet Phillanthus buxifolius Leaves as Feed Supplement]]>Wardah RahmahaniJola SopandiTatang 22016102Phyllantus buxifolius is an herbal feed supplement that can increase immunity and reduce cholesterol. A study has been conducted to investigate the effect diet of P. buxifolius leaves powder as feed supplement on mechanism of cholesterol reduction and increase immunity of quail. Seventy five quail at 30 day old randomly divided into 5 groups and each group fed leaves powder of P. buxifolius 0.0, 2.0, 4.0, 6.0 and 8.0% kg1 in commercial feed for 75 days, respectively. Powder of P. buxifolius leaves significantly (p<0.05) decreased fat, cholesterol and low density lipoprotein yolk egg quail but significantly increased High Density Lipoprotein (HDL) at measurement 45, 60 and 75 days old. Fed of 4.0 and 6.0% leaves of P. buxifolius powder significantly (p<0.05) increased the expression of interleukin-β and lymphocytes but significantly (p<0.05) decreased nitric oxide synthase (iNOS), leukocytes and monocytes even undetectable levels. Leaf powder of P. buxifolius potential as feed additive for decreasing fat and cholesterol yolk egg and increasing immunity of quail at 4-6% commercial feed. The use of this medicinal plant as a commercial feed supplementation can reduce quail mortality due to viral infection and may increase the interest of the market for the consumption of quail eggs.]]>Abbas, A.K., A.H.H. Lichtman and S. Pillai,20117th Edn.,Pages: 560Pages: 560Abdelwhab, E.M. and H.M. Hafez,2012431793208Adeneye, A.A., O.O. Amole and A.K. Adeneye,2006Phyllanthus amarus in mice.]]>77511514Czirjak, G., L. Kobolkuti, D. Cadar, A. Ungvari, M. Niculae and P. Bolfa,2007Coutrnix couternix Japonica).]]>64589589Dong, X.F., W.W. Gao, J.M. Tong, H.Q. Jia, R.N. Sa and Q. Zhang,20078619551959Doxey D.L. and M.B.F. Nathan,1989Fernendez, I.B., V.C. Cruz and G.V. Polycarpo,201183541Gonzales-Paramez, A.M., S. Esteban-Ruano, C. Santos-Buelga, S. Pascual-Teresa and J.C. Rivas-Gonzalo,200452234238Hsu, C.L. and G.C. Yen,20075584048410Hudson, J.B.,2009311891195Lima, F.S., E. Santin, A.C. Paulillo, L. Doretto Junior, V.M.B. de Moraes, N.M.Q. Gama and R.P. Schocken-Iturrino,2004Coturnix coturnix japonica).]]>3354356Matsui, Y., H. Kumagai and H. Masuda,2006125054Nurulhuda, M.H., A. Azlan, A. Ismail, Z. Amom and F.H. Shakirin,201278089Obianime, A.W. and F.I. Uche,2008Phyllanthus amarus leaf on the biochemical parameters of male guinea pigs.]]>127377Rodrigues, H.G., Y.S. Diniz, L.A. Faine, C.M. Galhardi and R.C. Burneiko et al.,2005567985Sa'idu, L., L.B. Tekdek and P.A. Abdu,200474309317Umbare, R.P., G.S. Mate, D.V. Jawalkar, S.M. Patil and S.S. Dongare,2009Phyllanthus amarus (Schumach) leaves extract for its hypolipidemic activity.]]>12833Wardah, T. and S. Wurlina,200768895Wardah, T. Sopandi, H.E. Bimo Aksono and Kusriningrum,2012Phyllanthus buxifolius.]]>6106117Jenkins, D.J.A., P.J.H. Jones, B. Lamarche, C.W.C. Kendall and D. Faulkner et al.,2011306831839Xia, D., X. Wu, Q. Yang, J. Gong and Y. Zhang,2010924632467Zhang, L.Z., Y.J. Guo, T.U. Gz, W.B. Guo and F. Miao,2000Phyllanthus urinaria L.]]>25615617Sopandi, T.,20052005Wardah,2011P. buxifolius) sebagai Imunostimulan Herbal Penurun Kolesterol Daging Ayam Broiler.]]>2011Panda, P. and R.P. Singh,199046219234