Asian Journal of Agricultural Research1819-1894xxxx-xxxxKnowledgia Review10.3923/ajar.2016.1.14AzzazHossam H. MorsyTarek A. MuradHussein A. 12016101Improved ruminants health and its productive performance has always remained a primary goal of researchers associated with the animal production sector. Microbial feed supplements as natural growth promoters might play an important role for enhancement of health and productive performance of ruminants through prevention of disease, enhancement of desirable microbial growth in the rumen environment, stabilization of ruminal pH, altered ruminal fermentation patterns, increased nutrient digestibility and flow of nutrients to the small intestine, improved nutrient retention and reduced stress through enhanced immune response. The definition of microbial feed supplements is very broad and may include specific and nonspecific yeast, fungi, bacteria, cell fragments and filtrates. The microbial feed supplements preparations must having a beneficial effect on the host animal (non-pathogenic and non-toxic), able to produce antimicrobial agents, antagonistic toward pathogenic, have ability to adhere and colonize the epithelial cells of the rumen and the gut, capable of compete with normal microflora and metabolizing in the gut environment and genetically stable and capable of remaining viable for long periods under storage and field conditions. The use of microbial feed supplements continuously may decrease the harmful effects of the pathogenic bacterial species in the ruminant digestive system and thereby improve the animal performance.]]>Abe, F., N. Ishibashi and S. Shimamura,19957828382846Abu-Tarboush, H.M., M.Y. Al-Saiady and A.H.K. El-Din,1996573949Adams, M.C., J. Luo, D. Rayward, S. King, R. Gibson and G.H. Moghaddam,20081454152Akin, D.E., G.L. Gordon and J.P. Hogan,1983Digitaria pentzii grown with or without sulfur.]]>46738748Arambel, M.J. and B.A. Kent,19907315601563Azzaz, H.H., A.M. Kholif, H.A. Murad, M.A. Hanfy and M.H. Abdel Gawad,20127664673Azzaz, H.H., H.A. Murad, A.M. Kholif, T.A. Morsy, A.M. Mansour and H.M. El-Sayed,201313234241Azzaz, H.H., H.A. Murad, A.M. Kholif, T.A. Morsy, A.M. Mansour and H.M. El-Sayed,201316117125Azzaz, H.H., H.A. Aziz, E.S.A. Farahat and H.A. Murad,201514567575Azzaz, H.H., H.M. Ebeid, T.A. Morsy and S.M. Kholif,201510107116Beauchemin, K.A., W.Z. Yang, D.P. Morgavi, G.R. Ghorbani, W. Kautz and J.A. Leedle,20038116281640Beharka, A.A. and T.G. Nagaraja,1998Aspergillus oryzae extract alone or in combination with antimicrobial compounds on ruminal bacteria.]]>8115911598Brandao, R.L., I.M. Castro, E.A. Bambirra, S.C. Amaral and L.G. Fietto et al.,1998Saccharomyces boulardii and Saccharomyces cerevisiae.]]>64564568Callaway, E.S. and S.A. Martin,1997Saccharomyces cerevisiae culture on ruminal bacteria that utilize lactate and digest cellulose.]]>8020352044Cartwright, C.P., J.R. Juroszek, M.J. Beavan, F.M.S. Ruby, S.M.F. de Morais and A.H. Rose,1986Saccharomyces cerevisiae.]]>132369377Collado, M.C., J. Meriluoto and S. Salminen,2007In vitro evaluation of different methods.]]>717174Dawson, K.A., K.E. Neuman and J.A. Boling,19906833923398Dawson, K.A.,19881988pp: 101pp: 101Dawson, K.A.,19921992pp: 1-23pp: 1-23Dicks, L. and M. Botes,201011129Elam, N.A., J.F. Gleghorn, J.D. Rivera, M.L. Galyean, P.J. Defoor, M.M. Brashears and S.M.Y. Dahl,2003Lactobacillus acidophilus (strains NP45 and NP51) and Ropionibacterium freudenreichii on performance, carcass and intestinal characteristics and Escherichia coli strain O157 shedding of finishing beef steers.]]>8126862698FAO/WHO.,20012001Farahat, E.S.A.,20142014Frizzo, L.S., L.P. Sotto, M.V. Zbrun, E. Bertozzi, G. Sequeira, R.R. Armesto and M.R. Rosmini,2010157159167Fuller, R.,198966365378Fuller, R.,19991999pp: 15-22pp: 15-22Gaafar, H.M.A., A.M.A. Mohi El-Din, M.I. Basiuoni and K.F.A. El-Riedy,200942188195Ghorbani, G.R., D.P. Morgavi, K.A. Beauchemin and J.A.Z. Leedle,20028019771985Gilliland, S.E., C.R. Nelson and C. Maxwell,1985Lactobacillus acidophilus.]]>49377381Goldin, B. and S.L. Gorbach,19774024212426Gomez-Basauri, J., M.B. de Ondarza and J. Siciliano-Jones,200184283283Guedes, C.M., D. Goncalves, M.A.M. Rodrigues and A. Dias-da-Silva,2007Saccharomyces cerevisiae yeast on ruminal fermentation and fibre degradation of maize silages in cows.]]>1452740Guillot, J.F.,2003265255Harris, Jr. B., H.H. Van Horn, S.P. Marshall, M.J. Taylor and C.J. Wilcox,1983Aspergillis oryzae product in complete rations for lactating cows.]]>6614741485Harrison, G.A., R.W. Hemken, K.A. Dawson, R.J. Harmon and K.B. Barker,19887129672975Huffman, RP., K.K. Karges, T.J. Klopfenstein, R.A. Stock, R.A. Britton and L.D. Roth,1992Lactobacillus acidophilus on subacute ruminal acidosis.]]>708787Isolauri, E., Y. Sutas, P. Kankaanpaa, H. Arvilommi and S. Salminen,200173444s450sJones, G.W. and J.M. Rutter,1972Escherichia coli in piglets.]]>6918927Jonsson, E. and I. Olsson,1985Lactobacillus strains to neonatal calves.]]>157176Jouany, J.P. and D.P. Morgavi,2007114431466Kilmer, L.,2000Knowlton, K.F., J.M. McKinney and C. Cobb,20028533283335Ko, S.Y. and C.J. Yang,20082113391347Kholif, A.M., H.A. El-Alamy, M.A. El-Ashry, H.M. El-Sayed and T.A. Ali,200028281295Krehbiel, C.R., S.R. Rust, G. Zhang and S.E. Gilliland,200381E120E132Kullen, M.J. and T.R. Klaenhammer,19991999pp: 65-83pp: 65-83Kung, L. and A.O. Hession,1995in vitro lactate accumulation in ruminal fermentations by inoculation with Megasphaera elsdenii.]]>73250256Lehloenya, K.V., D.R. Stein, D.T. Allen, G.E. Selk and D.A. Jones et al.,200892190202Lehloenya, K.V., C.R. Krehbiel, K.J. Mertz, T.G. Rehberger and L.J. Spicer,200891653662Lodge, S., T. Klopfenstein, R. Stock and D. Herold,19961996Lyons, T.P.,19901990pp: 1-9pp: 1-9Marco, M.L., S. Pavan and M. Kleerebezem,200617204210McPeake, C.A., C.S. Abney, K. Kizilkaya, M.L. Galyean and A.H. Trenkle et al.,20022002pp: 133Morsy, T.M., H.M. Ebeid, A.E.K.M. Kholif, H.A. Murad, A.E.R.M. Abd El-Gawad and T.M. Bedawy,201421319Murad, H.A. and H.H. Azzaz,2013Aspergillus flavus NRRL 5521.]]>1103107Newbold, C.J., R.J. Wallace and F.M. McIntosh,1996Saccharomyces cerevisiae as a feed additive for ruminants.]]>76249261Newbold, C.J., R. Brock and R.J. Wallace,1991Aspergillus oryzae fermentation extract on fermentation in the rumen simulation technique (Rusitec).]]>116159162Newman, K.E. and K.A. Jacques,19951995pp: 247-258pp: 247-258Nisbet, D.J. and S.A. Martin,1994Selenomonas ruminantium.]]>7213551361Nisbet, D.J. and S.A. Martin,1990Aspergillus oryzae fermentation extract on lactate uptake by the ruminal bacterium Selenomonas ruminantium.]]>5635153518Nissle, A.,1959E. coli therapy (mutaflor)].]]>410171022, (In German)Nocek, J.E., W.P. Kautz, J.A.Z. Leedle and J.G. Allman,2002in situ digestion in dairy cattle.]]>85429433Offer, N.W. and A. Cruive,19911991pp: 79pp: 79Panchal, C.J., I. Russell, A.M. Sills and C.G. Stewart,19843899106Parvez, S., K.A. Malik, S.A. Kang and H.Y. Kim,200610011711185Raeth-Knight, M.L., J.G. Linn and H.G. Jung,20079018021809Reiter, B. and B.G. Harnulv,198447724732Salem, F.A., A.S. Soliman, S.M. Abdelmawla and M.R.M. El-Mahdy,20003818851904Smith, H.W.,1971Escherichia coli infection.]]>176110125Stein, D.R., D.T. Allen, E.B. Perry, J.C. Bruner and K.W. Gates et al.,200689111125Swinney-Floyd, D., B.A. Gardner, F.N. Owens, T. Rehberger and T. Parrot,1999Propionibacterium strain P-63 alone or combined with Lactobacillus acidophilus strain LA53545 on performance of feedlot cattle.]]>77(Suppl. 1)7777Vandenbergh, P.A.,199312221238Varel, V.H., K.K. Kreikemeier, H.J.G. Jung and R.D. Hatfield,1993In vitro stimulation of forage fiber degradation by ruminal microorganisms with Aspergillus oryzae fermentation extract.]]>5931713176Waldrip, H.M. and S.A. Martin,1993Aspergillus oryzae fermentation extract and other factors on lactate utilization by the ruminal bacterium Megasphaera elsdenii.]]>7127702776Wallace, R.J., D. Colombatto and P.H. Robinson,200814514Walter, P.H., N. Weiss and W. Holzapfel,19921992pp: 1535-1573pp: 1535-1573Wilks, D.,19971997Williams, P.E.V.,19891989pp: 79-101pp: 79-101Williams, P.E.V., A. Walker and J.C. MacRae,1990Saccharomyces cerevisiae) plus growth medium) on duodenal protein flow in wether sheep.]]>49128A128AYang, W.Z., K.A. Beauchemin, D.D. Vedres, G.R. Ghorbani, D. Colombatto and D.P. Morgavi,2004114179193Yoon, I.K. and M.D. Stern,19958533555Pagan, J.,19901990Weidmir, R.D. and M.J. Arambel,1985Saccharomyces cerevisiae and/or Aspergillus oryzae on rumen function.]]>1985