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Pakistan Journal of Biological Sciences

Year: 2005 | Volume: 8 | Issue: 4 | Page No.: 527-531
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Research Article

Effect of Parquetina nigrescens on Erythrocyte Indices and Serum Electrolytes of Rats Following Acute Blood Loss

G.A. Agbor and A.A. Odetola

ABSTRACT

The effect of graded doses of aqueous leaf extract of Parquetina nigrescens on erythrocyte indices and serum electrolytes was studied for two weeks on rats following acute blood loss. Red blood cell count, haemoglobin concentration, haematocrit, reticulocyte population and erythrocyte osmofragility were used as erythrocyte indices. The plasma electrolytes concentrations of sodium, potassium, calcium and bicarbonate were analysed. Parquetina nigrescens significantly (p < 0.05) increased the erythrocyte indices which were initially reduced by bleeding except for erythrocyte osmofragility which instead decreased significantly (p < 0.05). Parquetina nigrescens had no effect on serum electrolyte except for sodium ion concentration which increased significantly (p < 0.05). The improved erythrocyte indices and reduced erythrocyte osmofragility are indications of erythropoietic potential of Parquetina nigrescens.
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