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Journal of Applied Sciences

Year: 2010 | Volume: 10 | Issue: 14 | Page No.: 1481-1484
DOI: 10.3923/jas.2010.1481.1484

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Authors


Jutti Levita

Country: Indonesia

As `ari Nawawi

Country: Indonesia

Abdul Mutholib

Country: Indonesia

Slamet Ibrahim

Country: Indonesia

Keywords


  • prostaglandin
  • human fibroblast cells
  • molecular modeling study
  • cyclooxygenase enzyme
  • Andrographolide
Research Article

Andrographolide Inhibits COX-2 Expression in Human Fibroblast Cells Due to its Interaction with Arginine and Histidine in Cyclooxygenase Site

Jutti Levita, As `ari Nawawi, Abdul Mutholib and Slamet Ibrahim
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Citations in impact factor journals

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Efficacy of Andrographis paniculata supplements induce a non-specific immune system against the pathogenicity of Aeromonas hydrophila infection in Indian major carp (Labeo rohita)
Environmental Science and Pollution Research
Combination therapy with andrographolide and d-penicillamine enhanced therapeutic advantage over monotherapy with d-penicillamine in attenuating fibrogenic response and cell death in the periportal zone of liver in rats during copper toxicosis
Toxicology and Applied Pharmacology Vol. 250, Issue 1, 54, 2011
Andrographolide Antagonizes TNF-α-induced IL-8 via Inhibition of NADPH Oxidase/ROS/NF-κB and Src/MAPKs/AP-1 Axis in Human Colorectal Cancer HCT116 Cells
Journal of Agricultural and Food Chemistry
An in vitro study of anti-inflammatory activity of standardised Andrographis paniculata extracts and pure andrographolide
BMC Complementary and Alternative Medicine Vol. 15, Issue 1, , 2015
Andrographolide: A Review of its Anti-inflammatory Activity via Inhibition of NF-kappaB Activation from Computational Chemistry Aspects
International Journal of Pharmacology Vol. 6, Issue 5, 569, 2010

Citation to this article as recorded by ASCI logo

Antre, R.V., A. Cendilkumar, D. Goli, P.M. Gurubasavrajswamy and R.J. Oswal, 2012. Molecular docking studies of substituted pyrazolone derivatives as cytokine synthesis inhibitors. Am. J. Biochem. Mol. Biol., 2: 183-189.
CrossRefDirect Link

Levita, J., A. Nawawi, A. Mutalib and S. Ibrahim, 2010. Andrographolide: A review of its anti-inflammatory activity via inhibition of NF-kappaB activation from computational chemistry aspects. Int. J. Pharmacol., 6: 569-576.
CrossRefDirect Link

Levita, J., D. Rahayu, N.M. Saptarini, A. Nawawi, A. Mutalib and S. Ibrahim, 2011. The inhibition of andrographolide (Andrographis paniculata) on the expression of carbonic anhydrase in LPS-induced human leucocyte cells. Asian J. Plant Sci., 10: 162-165.
CrossRefDirect Link

Citation to this article as recorded by Crossref logo

Effect of dietary Andrographis paniculata leaf extract on growth, immunity, and disease resistance against Aeromonas hydrophila in Pangasianodon hypopthalmus
Journal of Applied Aquaculture
A Report on Multi-Target Anti-Inflammatory Properties of Phytoconstituents from Monochoria hastata (Family: Pontederiaceae)
Molecules Vol. 26, Issue 23, 7397, 2021
Molecular Docking Studies of Substituted Pyrazolone Derivatives as Cytokine Synthesis Inhibitors
American Journal of Biochemistry and Molecular Biology Vol. 2, Issue 3, 183, 2012
The Inhibition of Andrographolide (Andrographis paniculata) on the Expression of Carbonic Anhydrase in LPS-Induced Human Leucocyte Cells
Asian Journal of Plant Sciences Vol. 10, Issue 2, 162, 2011

How to cite this article

Jutti Levita, As `ari Nawawi, Abdul Mutholib and Slamet Ibrahim, 2010. Andrographolide Inhibits COX-2 Expression in Human Fibroblast Cells Due to its Interaction with Arginine and Histidine in Cyclooxygenase Site. Journal of Applied Sciences, 10: 1481-1484.

DOI: 10.3923/jas.2010.1481.1484

URL: https://scialert.net/abstract/?doi=jas.2010.1481.1484

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