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Pakistan Journal of Nutrition

Year: 2016 | Volume: 15 | Issue: 4 | Page No.: 370-373
DOI: 10.3923/pjn.2016.370.373
Effect of Modified Diet and Exercise on Insulin Level in Diabetes Mellitus Type-2 Patients
Masrul , Eva Decroli, Idral Purnakarya and Nur Indrawaty Lipoeto

Abstract: Diabetes Mellitus type-2 is a chronic degenerative disease with an increasing prevalence and incidence rate. Obesity and insulin resistance have been confirmed as the main causes. This study aims to understand the effect of modified diet and exercise to insulin level in diabetes mellitus type-2 patients. This was a comparative experimental study to modify body weight in diabetes mellitus type-2 patients with obesity in a diabetic clinic of Dr. M Djamil Hospital, from January until December 2010. Subjects in the treatment group received the consultation regarding exercise and modified diet for six months whereas subjects in the control group did not get any intervention. Then, in the end of the study, the BMI, fasting glucose and insulin level were measured in both groups. We found a significant difference in protein intake in both groups. We also found a significant difference in insulin level before and after the treatment (12.24±9.21 μU/ml and 8.58±4.40 μU/ml; p = 0.035, respectively). There is no significant difference in reduction of blood glucose level in both groups. We suggest to further research to see the role of glycemic index to blood glucose level in diabetes mellitus type-2 patients and distribution of information in community about the role of modified diet and exercise to reduce obesity in diabetes patients.

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How to cite this article
Masrul , Eva Decroli, Idral Purnakarya and Nur Indrawaty Lipoeto, 2016. Effect of Modified Diet and Exercise on Insulin Level in Diabetes Mellitus Type-2 Patients. Pakistan Journal of Nutrition, 15: 370-373.

Keywords: Diabetes mellitus type-2, obesity, glucose level, insulin level and BMI

REFERENCES

  • Barry, J.G. and D. Muller-Wieland, 2008. Type 2 Diabetes: Prinsip and Practice. Informa Health care Inc., New York, USA


  • CBSI., 2005. The life expectancy of the population of some countries in 1955-2015. Central Bureau of Statistic, Jakarta, Indonesia.


  • Froguel, P. and G. Velho, 2001. Genetic determinants of type 2 diabetes. Recent Prog. Hormone Res., 56: 91-105.
    Direct Link    


  • Furukawa, S., T. Fujita, M. Shimabukuro, M. Iwaki and Y. Yamada et al., 2004. Increased oxidative stress in obesity and its impact on metabolic syndrome. J. Clin. Invest., 114: 1752-1761.
    CrossRef    PubMed    Direct Link    


  • Goodpaster, B.H., F.L. Thaete and D.E. Kelley, 2000. Thigh adipose tissue distribution is associated with insulin resistance in obesity and in type 2 diabetes mellitus. Am. J. Clin. Nutr., 71: 885-892.
    Direct Link    


  • Tjokroprawiro, A., 1983. Diabetes Mellitus in the Municipality of Surabaya, Indonesia. In: Preceeding of the 4th International Seminar on Diabetes Mellitus and Nutrition: Diabetes Mellitus as Related to Over and Under Nutrition, Baba, S., S. Iwai and U. Sukaton (Eds.). International Center for Medical Research. Kobe University School of Medicine, Kobe, Japan, pp: 22-23


  • Schelenker, E.D., S. Long and S. William, 2007. Essentials of Nutrition and Diet Theraphy. 9th Edn., Mosby Elsevier, Misisouri


  • Schenk, S., M. Saberi and J.M. Olefsky, 2008. Insulin sensitivity: Modulation by nutrients and inflammation. J. Clin. Invest., 118: 2992-3002.
    CrossRef    Direct Link    


  • Sutanegara, D. and A.A.G. Budhiarta, 2000. The epidemiology and management of diabetes mellitus in Indonesia. Diabetes Res. Clin. Pract., 50: S9-S16.
    CrossRef    Direct Link    


  • Wild, S., G. Roglic, A. Green, R. Sicree and H. King, 2004. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care, 27: 1047-1053.
    CrossRef    PubMed    Direct Link    

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